HitPredict

Interactor 1: S100B (P04271)
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)
Gene: S100B

Interactor 2: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005654 - nucleoplasm GO:0043025 - neuronal cell body
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 973
+	Hs
		638928 S100P_HUMAN (1-91): 2.35e-34: 114: 50.55		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		685156 S10AB_HUMAN (2-91): 3e-33: 112: 35.56		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		615205 S10A1_HUMAN (2-89): 2.93e-33: 111: 60.23		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		642918 S10A4_HUMAN (3-90): 2.3e-30: 104: 47.73		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		416365 S10A9_HUMAN (1-91): 3.59e-29: 102: 36.96		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		661206 S10A2_HUMAN (2-90): 1.34e-29: 102: 44.94		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689702 S10AA_HUMAN (2-89): 2.16e-29: 102: 38.64		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689703 S10AC_HUMAN (1-92): 2.11e-29: 102: 38.04		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689707 S100Z_HUMAN (2-92): 4.09e-29: 101: 45.06		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689700 S10A3_HUMAN (3-90): 1.74e-28: 100: 38.64		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		396691 S10A8_HUMAN (1-92): 4.18e-25: 91.4: 32.61		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		416580 S10A6_HUMAN (3-90): 7.15e-24: 87.9: 39.77		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689699 S10A5_HUMAN (2-92): 2.82e-22: 84.1: 39.56		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689708 S10AD_HUMAN (1-83): 3.55e-21: 81.4: 28.92		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689709 S10AE_HUMAN (2-83): 1.74e-19: 77.5: 29.27		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689706 S1A7A_HUMAN (2-90): 1.7e-18: 74.8: 25.28		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		666669 S100G_HUMAN (6-83): 6.77e-17: 70.3: 34.62		NAC1_HUMAN (1-973): 0: 1131: 100.00