HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.80	0.638

Property	Details
Experiments	22319573, unassigned4
Identification Methods	affinity chromatography technology, experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~WD40
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 136 Dm			1 730
+	Hs
		998238 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89
+	Hs
		998825 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		GBB4_HUMAN (471-729): 8.45e-61: 209: 16.79
+	Hs
		992684 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		RACK1_HUMAN (525-728): 1.23e-53: 189: 20.83
+	Hs
		984069 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		GBB2_HUMAN (506-728): 6.31e-51: 182: 17.39
+	Hs
		845310 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		LIS1_HUMAN (603-728): 1.46e-32: 132: 21.09
+	Hs
		998532 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		DAW1_HUMAN (616-728): 7.12e-30: 124: 13.79
+	Hs
		209245 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		PRP4_HUMAN (571-728): 1.42e-23: 107: 15.39
+	Hs
		964837 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		WDR5_HUMAN (316-470): 1.17e-13: 74.9: 7.98
+	Hs
		964848 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		WDR5_HUMAN (316-470): 1.17e-13: 74.9: 7.98
+	Hs
		964981 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		WDR5_HUMAN (316-470): 1.17e-13: 74.9: 7.98