Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2
Interactor 2: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.33 | 1.00 | 0.575 |
The method score is based on:
Property | Details |
---|---|
Experiments | 9461599 |
Identification Methods | competition binding |
Interaction Type | association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1 |
Common GO terms | GO:0004713 - protein tyrosine kinase activity GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006468 - protein phosphorylation and 1 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
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Last updated: 15 Jul 2024