HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25921289, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 543
+	Hs
		385407 NTRK1_HUMAN (1-796): 0: 621: 100.00		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		385527 NTRK1_HUMAN (1-796): 0: 621: 100.00		RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14
+	Hs
		385317 NTRK1_HUMAN (1-796): 0: 621: 100.00		TTC28_HUMAN (196-538): 5.68e-18: 90.3: 12.86
+	Hs
		174540 NTRK1_HUMAN (1-796): 0: 621: 100.00		OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57
+	Hs
		297020 NTRK1_HUMAN (1-796): 0: 621: 100.00		TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00
+	Hs
		608096 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		609403 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		TMTC1_HUMAN (2-318): 1.14e-31: 132: 13.25
+	Rn
		193482 INSR_RAT (493-777): 7.31e-66: 241: 41.95		STIP1_RAT (1-543): 1.66e-96: 305: 97.61
+	Hs
		434258 RET_HUMAN (391-794): 3.5e-114: 374: 30.44		SGTB_HUMAN (213-348): 5.73e-32: 126: 31.39