Protein: OAT
Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine delta-aminotransferase) (Ornithine--oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form]

Gene: OAT
Organism: Homo sapiens
Interactions: 161
UniProt ID: P04181

Gene Ontology (top 5):
GO:0004587 - ornithine aminotransferase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226228

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

262670

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.584

High

378583

ANLN
Anillin

2

0

High-throughput

0.559

High

378481

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

378553

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.518

High

378563

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

378498

CCNF
Cyclin-F

1

1

High-throughput

0.515

High

378499

5HT2B
5-hydroxytryptamine receptor 2B

1

1

High-throughput

0.515

High

378521

DMWD
Dystrophia myotonica WD repeat-containing protein

1

1

High-throughput

0.515

High

378469

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

201170

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

343931

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.513

High

345655

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.513

High

378476

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

378492

MYH9
Myosin-9

1

0

High-throughput

0.513

High

378496

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

378504

ANX11
Annexin A11

1

0

High-throughput

0.513

High

378518

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

378526

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

378531

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

378533

MYLK
Myosin light chain kinase, smooth muscle

1

0

High-throughput

0.513

High

378535

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

378546

COX15
Heme A synthase COX15

1

0

High-throughput

0.513

High

378565

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

378587

UBQL4
Ubiquilin-4

1

7

High-throughput

0.508

High

378505

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.493

High

378516

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.493

High

197179

SERA
D-3-phosphoglycerate dehydrogenase

1

2

High-throughput

0.489

High

378514

KC1G2
Casein kinase I isoform gamma-2

1

2

High-throughput

0.489

High

378519

CALD1
Caldesmon

1

1

High-throughput

0.489

High

378559

FAF2
FAS-associated factor 2

1

1

High-throughput

0.489

High

329066

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.486

High

174536

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

260512

TP4A3
Protein tyrosine phosphatase type IVA 3

1

1

High-throughput

0.479

High

264810

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

324981

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

326369

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.479

High

337742

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

378475

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

378479

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

378483

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

378485

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

378486

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.479

High

378494

BASI
Basigin

1

1

High-throughput

0.479

High

378509

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

378512

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.479

High

378513

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

4

Small-scale

0.479

High

378522

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

378525

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.479

High

378528

CUL3
Cullin-3

1

1

High-throughput

0.479

High

378529

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

378536

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

2

High-throughput

0.479

High

378538

SMU1
WD40 repeat-containing protein SMU1

1

2

High-throughput

0.479

High

378539

ANR55
Ankyrin repeat domain-containing protein 55

1

1

High-throughput

0.479

High

378544

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

378560

OPTN
Optineurin

1

1

High-throughput

0.479

High

378569

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

378572

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

378577

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

378578

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.479

High

378590

HDAC6
Histone deacetylase 6

1

2

High-throughput

0.479

High

378591

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

378592

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

378593

UBQL2
Ubiquilin-2

1

4

High-throughput

0.479

High

378594

FAF1
FAS-associated factor 1

1

1

High-throughput

0.479

High

378595

NSF1C
NSFL1 cofactor p47

1

1

Small-scale

0.479

High

378596

HDAC5
Histone deacetylase 5

1

2

High-throughput

0.479

High

378602

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

879

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.464

High

59082

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

119073

LEG9
Galectin-9

1

0

High-throughput

0.458

High

241930

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

322056

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

378474

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

378477

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

378482

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

378487

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

378490

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

378491

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

378495

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

378497

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

378500

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

378501

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

378502

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

378503

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

378506

EPIPL
Epiplakin

1

0

High-throughput

0.458

High

378507

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

378508

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

378515

CCNA1
Cyclin-A1

1

0

High-throughput

0.458

High

378517

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

378520

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

378523

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

378524

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.458

High

378527

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

378530

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

378532

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

378534

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

378537

DUS6
Dual specificity protein phosphatase 6

1

0

High-throughput

0.458

High

378540

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

378542

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

378548

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

378549

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

378550

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

378551

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

378555

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

378558

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

378561

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

378564

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

378566

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.458

High

378567

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

378568

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

378571

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

378573

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

378574

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

378576

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

378579

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

378580

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

378581

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.458

High

378584

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

378585

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

378589

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

378598

FND3A
Fibronectin type-III domain-containing protein 3A

1

0

High-throughput

0.458

High

378599

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

Small-scale

0.458

High

378600

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

378601

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

378470

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

378478

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

378484

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.445

High

378541

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

378543

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

378588

SPHK1
Sphingosine kinase 1

1

1

Small-scale

0.445

High

378586

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

239474

EIF1B
Eukaryotic translation initiation factor 1b

1

1

High-throughput

0.437

High

378467

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

378471

INSR
Insulin receptor

1

2

High-throughput

0.437

High

378472

ADRB2
Beta-2 adrenergic receptor

1

1

High-throughput

0.437

High

378473

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

2

High-throughput

0.437

High

378488

UFO
Tyrosine-protein kinase receptor UFO

1

2

High-throughput

0.437

High

378552

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

378480

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

378489

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

378554

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

378562

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

99539

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

378557

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.282

High

173419

RER1
Protein RER1

1

0

High-throughput

0.279

Low

378493

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

378547

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

378556

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.279

Low

378582

RTN4
Reticulon-4

1

0

High-throughput

0.279

Low

257306

CNOT3
CCR4-NOT transcription complex subunit 3

1

0

High-throughput

0.269

Low

224894

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.249

Low

273339

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.249

Low

354247

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

378468

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

378510

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

378511

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.249

Low

378570

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.249

Low

378545

NEK10
Serine/threonine-protein kinase Nek10

1

0

High-throughput

0.232

Low

378575

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

0

High-throughput

0.232

Low

378597

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024