HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007411 - axon guidance GO:0030424 - axon GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 450
+	Hs
		384107 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		384633 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		385452 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB2B_HUMAN (1-430): 0: 703: 93.72
+	Hs
		385445 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		508174 FGFR1_HUMAN (195-794): 0: 545: 26.34		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		381109 FGFR1_HUMAN (195-794): 0: 545: 26.34		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		1081592 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		537737 INSRR_HUMAN (493-782): 6.64e-66: 241: 42.91		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		435747 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		411272 INSR_HUMAN (493-777): 3e-68: 248: 42.62		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		968471 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		934024 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		TBB4B_HUMAN (1-427): 0: 703: 93.91