Protein: OTX2
Homeobox protein OTX2 (Orthodenticle homolog 2)

Gene: OTX2
Organism: Homo sapiens
Interactions: 56
UniProt ID: P32243

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686549

ATX1
Ataxin-1

3

9

High-throughput

0.676

High

686545

OTX2
Homeobox protein OTX2

1

16

Small-scale

0.647

High

686548

LHX1
LIM/homeobox protein Lhx1

1

18

Small-scale

0.647

High

686553

PO5F1
POU domain, class 5, transcription factor 1

1

20

High-throughput

0.618

High

686582

NANOG
Homeobox protein NANOG

1

18

High-throughput

0.618

High

686586

AURKC
Aurora kinase C

2

9

High-throughput

0.615

High

47751

RBM47
RNA-binding protein 47

2

2

High-throughput

0.606

High

446521

SNRPA
U1 small nuclear ribonucleoprotein A

2

3

High-throughput

0.606

High

686546

HNF1B
Hepatocyte nuclear factor 1-beta

2

20

High-throughput

0.606

High

686550

KLF3
Krueppel-like factor 3

2

11

High-throughput

0.606

High

686552

CDK3
Cyclin-dependent kinase 3

2

8

High-throughput

0.606

High

686565

ZN765
Zinc finger protein 765

2

1

High-throughput

0.606

High

686575

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

1

High-throughput

0.606

High

394200

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.602

High

686587

FOXA2
Hepatocyte nuclear factor 3-beta

2

13

Small-scale

0.602

High

128710

RTCA
RNA 3'-terminal phosphate cyclase

2

0

High-throughput

0.580

High

155538

TNPO2
Transportin-2

2

0

High-throughput

0.580

High

199174

ZNHI1
Zinc finger HIT domain-containing protein 1

2

0

High-throughput

0.580

High

686547

IQGA1
Ras GTPase-activating-like protein IQGAP1

2

0

High-throughput

0.580

High

686560

HIKES
Protein Hikeshi

2

0

High-throughput

0.580

High

686562

TM10B
tRNA methyltransferase 10 homolog B

2

0

High-throughput

0.580

High

686572

TET5B
Terminal nucleotidyltransferase 5B

2

0

High-throughput

0.580

High

686580

NAA50
N-alpha-acetyltransferase 50

2

0

High-throughput

0.580

High

686584

JUPI1
Jupiter microtubule associated homolog 1

2

0

High-throughput

0.580

High

515351

CDK4
Cyclin-dependent kinase 4

1

12

Small-scale

0.569

High

686551

RS26
Small ribosomal subunit protein eS26

2

2

High-throughput

0.553

High

686555

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

2

High-throughput

0.553

High

686561

TBCEL
Tubulin-specific chaperone cofactor E-like protein

2

3

High-throughput

0.553

High

686570

M1AP
Meiosis 1 arrest protein

2

2

High-throughput

0.553

High

686576

VATG3
V-type proton ATPase subunit G 3

2

1

High-throughput

0.553

High

686577

OR6C1
Olfactory receptor 6C1

2

2

High-throughput

0.553

High

686583

HOME3
Homer protein homolog 3

2

4

High-throughput

0.553

High

686585

GUC1B
Guanylyl cyclase-activating protein 2

2

1

High-throughput

0.553

High

686554

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.541

High

686564

DDX46
Probable ATP-dependent RNA helicase DDX46

1

2

High-throughput

0.536

High

686589

DDX49
Probable ATP-dependent RNA helicase DDX49

1

4

High-throughput

0.536

High

686556

PAK1
Serine/threonine-protein kinase PAK 1

1

8

High-throughput

0.515

High

534070

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.513

High

416938

IF4E
Eukaryotic translation initiation factor 4E

1

1

Small-scale

0.501

High

686566

ZDH17
Palmitoyltransferase ZDHHC17

1

11

High-throughput

0.494

High

686558

MAP7
Ensconsin

1

17

High-throughput

0.489

High

686573

RMXL1
RNA binding motif protein, X-linked-like-1

1

1

High-throughput

0.489

High

686579

PDIP3
Polymerase delta-interacting protein 3

1

2

High-throughput

0.481

High

686563

BCOR
BCL-6 corepressor

1

10

High-throughput

0.479

High

686571

Q8WUT1
POLDIP3 protein

1

2

High-throughput

0.470

High

686578

SORT
Sortilin

1

1

High-throughput

0.437

High

565342

TMM11
Transmembrane protein 11, mitochondrial

2

0

High-throughput

0.316

High

686567

OR1L3
Olfactory receptor 1L3

2

0

High-throughput

0.316

High

686568

B4GN2
Beta-1,4 N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.316

High

686569

RNS11
Probable ribonuclease 11

2

0

High-throughput

0.316

High

686574

ASIC4
Acid-sensing ion channel 4

2

0

High-throughput

0.316

High

686581

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

0

High-throughput

0.316

High

686588

GPR45
Probable G-protein coupled receptor 45

2

0

High-throughput

0.316

High

686559

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

686557

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024