HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 1382
+	Hs
		384384 NTRK1_HUMAN (1-796): 0: 621: 100.00		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		384385 NTRK1_HUMAN (1-796): 0: 621: 100.00		MYH10_HUMAN (46-929): 1.09e-34: 147: 10.53
+	Hs
		384641 NTRK1_HUMAN (1-796): 0: 621: 100.00		MAP1A_HUMAN (494-1117): 2.75e-30: 133: 13.68
+	Hs
		508233 FGFR1_HUMAN (195-794): 0: 545: 26.34		ITSN2_HUMAN (542-870): 1.01e-49: 196: 21.46
+	Hs
		385802 NTRK1_HUMAN (1-796): 0: 621: 100.00		MRCKB_HUMAN (610-1132): 1.14e-14: 82: 10.96
+	Hs
		608159 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		ITSN2_HUMAN (542-870): 1.01e-49: 196: 21.46
+	Hs
		384210 NTRK1_HUMAN (1-796): 0: 621: 100.00		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		601605 FGFR2_HUMAN (87-794): 5.67e-159: 484: 22.55		ITSN2_HUMAN (542-870): 1.01e-49: 196: 21.46
+	Hs
		508022 FGFR1_HUMAN (195-794): 0: 545: 26.34		ITSN1_HUMAN (539-880): 4.76e-22: 106: 18.54
+	Hs
		508011 FGFR1_HUMAN (195-794): 0: 545: 26.34		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		607984 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		ITSN1_HUMAN (539-880): 4.76e-22: 106: 18.54
+	Hs
		665375 EPHA3_HUMAN (262-788): 8.75e-112: 365: 26.64		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		725069 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		725268 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		MYH10_HUMAN (46-929): 1.09e-34: 147: 10.53
+	Rn
		94275 INSR_RAT (493-777): 7.31e-66: 241: 41.95		F1LUA1_RAT (643-1382): 6.64e-29: 128: 5.94
+	Hs
		968305 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97