HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: GGA2 (Q9UJY4)
ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear)
Gene: GGA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26446845
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane GO:0031901 - early endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Hs			1 613
+	Hs
		508256 FGFR1_HUMAN (195-794): 0: 545: 26.34		GGA2_HUMAN (12-613): 0: 556: 100.00
+	Hs
		385689 NTRK1_HUMAN (1-796): 0: 621: 100.00		GGA1_HUMAN (19-612): 1.68e-159: 473: 44.67
+	Rn
		88616 NTRK1_RAT (1-796): 0: 592: 85.61		D3ZHG8_RAT (21-611): 4.4e-159: 472: 40.30
+	Hs
		608177 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		GGA2_HUMAN (12-613): 0: 556: 100.00
+	Hs
		508257 FGFR1_HUMAN (195-794): 0: 545: 26.34		GGA1_HUMAN (19-612): 1.68e-159: 473: 44.67
+	Hs
		212583 NTRK1_HUMAN (1-796): 0: 621: 100.00		AP1G1_HUMAN (44-610): 7.48e-109: 347: 17.44
+	Hs
		241132 NTRK1_HUMAN (1-796): 0: 621: 100.00		TOM1_HUMAN (23-495): 1.66e-100: 316: 19.02
+	Hs
		276985 NTRK1_HUMAN (1-796): 0: 621: 100.00		STAM2_HUMAN (19-521): 4.17e-99: 313: 17.66
+	Hs
		385279 NTRK1_HUMAN (1-796): 0: 621: 100.00		STAM1_HUMAN (19-524): 3.22e-96: 306: 15.76
+	Hs
		276996 FGFR1_HUMAN (195-794): 0: 545: 26.34		STAM2_HUMAN (19-521): 4.17e-99: 313: 17.66
+	Hs
		508131 FGFR1_HUMAN (195-794): 0: 545: 26.34		STAM1_HUMAN (19-524): 3.22e-96: 306: 15.76
+	Hs
		277074 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		STAM2_HUMAN (19-521): 4.17e-99: 313: 17.66
+	Hs
		277073 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		STAM2_HUMAN (19-521): 4.17e-99: 313: 17.66
+	Hs
		1081556 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		STAM1_HUMAN (19-524): 3.22e-96: 306: 15.76
+	Hs
		277003 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		STAM2_HUMAN (19-521): 4.17e-99: 313: 17.66
+	Hs
		608072 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		STAM1_HUMAN (19-524): 3.22e-96: 306: 15.76
+	Hs
		385624 NTRK1_HUMAN (1-796): 0: 621: 100.00		GGA3_HUMAN (328-611): 1.6e-47: 179: 32.33
+	Hs
		508231 FGFR1_HUMAN (195-794): 0: 545: 26.34		GGA3_HUMAN (328-611): 1.6e-47: 179: 32.33
+	Hs
		1081629 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		GGA3_HUMAN (328-611): 1.6e-47: 179: 32.33
+	Hs
		608158 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		GGA3_HUMAN (328-611): 1.6e-47: 179: 32.33