HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: FYV1 (Q9Y2I7)
1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1)
Gene: PIKFYVE

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0010008 - endosome membrane GO:0031901 - early endosome membrane GO:0031902 - late endosome membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 2098
+	Hs
		384470 NTRK1_HUMAN (1-796): 0: 621: 100.00		TCPE_HUMAN (449-995): 6.65e-167: 524: 14.80
+	Hs
		384227 NTRK1_HUMAN (1-796): 0: 621: 100.00		TCPA_HUMAN (470-1004): 9.34e-162: 511: 12.77
+	Hs
		384479 NTRK1_HUMAN (1-796): 0: 621: 100.00		TCPG_HUMAN (459-1010): 6.42e-159: 502: 17.35
+	Hs
		384509 NTRK1_HUMAN (1-796): 0: 621: 100.00		TCPD_HUMAN (449-990): 1.17e-145: 465: 16.19