HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	38580884, 23443559, 17936559
Identification Methods	proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 229
+	Hs
		385967 P53_HUMAN (1-393): 0: 619: 100.00		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Rn
		488473 P53_RAT (1-393): 0: 572: 77.02		UBC_RAT (1-181): 2.6e-61: 206: 96.13
+	Hs
		386475 P53_HUMAN (1-393): 0: 619: 100.00		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		171471 P53_HUMAN (1-393): 0: 619: 100.00		UBD_HUMAN (79-228): 1.03e-29: 110: 31.41
+	Hs
		175814 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		398093 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		ISG15_HUMAN (3-154): 1.46e-26: 102: 32.26