Protein: CERS3
Ceramide synthase 3 (CerS3) (Dihydroceramide synthase 3) (LAG1 longevity assurance homolog 3) (Sphingosine N-acyltransferase CERS3) (EC 2.3.1.24) (Ultra-long-chain ceramide synthase CERS3) (EC 2.3.1.298) (Very-long-chain ceramide synthase CERS3) (EC 2.3.1.297)

Gene: CERS3
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q8IU89

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0008544 - epidermis development
GO:0030148 - sphingolipid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1306976

ORML3
ORM1-like protein 3

2

2

High-throughput

0.606

High

1306981

NEUR1
Sialidase-1

2

1

High-throughput

0.553

High

1306983

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

2

1

High-throughput

0.553

High

1306985

S39A9
Zinc transporter ZIP9

2

8

High-throughput

0.553

High

387730

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

2

High-throughput

0.536

High

387852

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

2

High-throughput

0.536

High

457879

INVO
Involucrin

1

1

High-throughput

0.536

High

1037005

DSC2
Desmocollin-2

1

1

High-throughput

0.536

High

1306978

EVPL
Envoplakin

1

3

High-throughput

0.536

High

1306979

KLK6
Kallikrein-6

1

4

High-throughput

0.536

High

1306987

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.536

High

126243

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.513

High

483929

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.513

High

1191771

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.513

High

1306982

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.513

High

210763

KLK10
Kallikrein-10

1

4

High-throughput

0.489

High

369885

CO3
Complement C3

1

2

High-throughput

0.489

High

387986

FIBG
Fibrinogen gamma chain

1

2

High-throughput

0.489

High

474797

VIME
Vimentin

1

4

High-throughput

0.489

High

551623

NFH
Neurofilament heavy polypeptide

1

4

High-throughput

0.489

High

568965

ANXA8
Annexin A8

1

1

High-throughput

0.489

High

692225

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

1

High-throughput

0.489

High

706205

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

713411

SPB3
Serpin B3

1

2

High-throughput

0.489

High

748650

DSG3
Desmoglein-3

1

1

High-throughput

0.489

High

874814

SPB4
Serpin B4

1

2

High-throughput

0.489

High

945816

EPIPL
Epiplakin

1

3

High-throughput

0.489

High

1031110

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

1

High-throughput

0.489

High

1286335

S1A7A
Protein S100-A7A

1

1

High-throughput

0.489

High

1294065

PA24D
Cytosolic phospholipase A2 delta

1

2

High-throughput

0.489

High

1306986

IL36G
Interleukin-36 gamma

1

2

High-throughput

0.489

High

1306988

I36RA
Interleukin-36 receptor antagonist protein

1

2

High-throughput

0.489

High

1306989

IL36A
Interleukin-36 alpha

1

2

High-throughput

0.489

High

1306991

SPB13
Serpin B13

1

2

High-throughput

0.489

High

1306980

Q96FB2
SLC29A2 protein

1

3

High-throughput

0.470

High

1127887

S29A2
Equilibrative nucleoside transporter 2

1

3

High-throughput

0.439

High

75689

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

2

High-throughput

0.437

High

658967

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

3

High-throughput

0.437

High

49206

IGLC7
Immunoglobulin lambda constant 7

1

7

High-throughput

0.407

High

69514

A2ML1
Alpha-2-macroglobulin-like protein 1

1

2

High-throughput

0.407

High

379113

IGKC
Immunoglobulin kappa constant

1

7

High-throughput

0.407

High

379272

IGHG1
Immunoglobulin heavy constant gamma 1

1

7

High-throughput

0.407

High

379369

IGHG2
Immunoglobulin heavy constant gamma 2

1

6

High-throughput

0.407

High

379432

IGHG3
Immunoglobulin heavy constant gamma 3

1

7

High-throughput

0.407

High

379464

IGHG4
Immunoglobulin heavy constant gamma 4

1

7

High-throughput

0.407

High

379544

IGHM
Immunoglobulin heavy constant mu

1

6

High-throughput

0.407

High

133188

QSOX1
Sulfhydryl oxidase 1

1

0

High-throughput

0.279

Low

238670

AK1BA
Aldo-keto reductase family 1 member B10

1

0

High-throughput

0.279

Low

325334

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

592858

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.279

Low

609315

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

627137

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

868729

LEG7
Galectin-7

1

0

High-throughput

0.279

Low

1009675

NGAL
Neutrophil gelatinase-associated lipocalin

1

0

High-throughput

0.279

Low

1023825

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.279

Low

1120919

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

1306977

NDRG1
Protein NDRG1

1

0

High-throughput

0.279

Low

1306984

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.279

Low

1306990

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

1306992

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.279

Low

1306993

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025