HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.754

The method score is based on:

Property	Details
Experiments	7954368, 28215707, 8940078, 31027880, 8729618, 25144556, 11707401, 31152661, 32807901, 11297531, 36749630, 23443559
Identification Methods	affinity chromatography technology, unspecified method, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol and 7 others more... GO:0006606 - protein import into nucleus GO:0019899 - enzyme binding GO:0021549 - cerebellum development GO:0031625 - ubiquitin protein ligase binding GO:0045892 - negative regulation of DNA-templated transcription GO:0051087 - protein-folding chaperone binding GO:0051726 - regulation of cell cycle
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	646

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024