Protein: IQUB
IQ motif and ubiquitin-like domain-containing protein

Gene: IQUB
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q8NA54

Gene Ontology (top 5):
GO:0001534 - radial spoke
GO:0001669 - acrosomal vesicle
GO:0007224 - smoothened signaling pathway
GO:0007618 - mating
GO:0030317 - flagellated sperm motility

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1332369

TRI54
Tripartite motif-containing protein 54

3

4

High-throughput

0.766

High

783334

TRI23
E3 ubiquitin-protein ligase TRIM23

4

0

High-throughput

0.754

High

1294318

TRI50
E3 ubiquitin-protein ligase TRIM50

2

1

High-throughput

0.700

High

1332387

TRAF6
TNF receptor-associated factor 6

2

3

High-throughput

0.700

High

1332351

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

High-throughput

0.663

High

1090796

TRAF2
TNF receptor-associated factor 2

1

1

High-throughput

0.662

High

1311439

TRI42
Tripartite motif-containing protein 42

1

4

High-throughput

0.662

High

250292

VINEX
Vinexin

2

0

High-throughput

0.655

High

1332367

KATL1
Katanin p60 ATPase-containing subunit A-like 1

2

0

High-throughput

0.655

High

1332378

APC11
Anaphase-promoting complex subunit 11

2

0

High-throughput

0.655

High

1332381

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.655

High

1332362

TRI63
E3 ubiquitin-protein ligase TRIM63

1

4

High-throughput

0.625

High

1332370

TRI55
Tripartite motif-containing protein 55

1

3

High-throughput

0.625

High

1053256

Q05BL1
TP53BP2 protein

1

1

High-throughput

0.594

High

1315735

SAXO1
Stabilizer of axonemal microtubules 1

2

0

High-throughput

0.580

High

1332352

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.580

High

1332372

BTBD1
BTB/POZ domain-containing protein 1

2

1

High-throughput

0.574

High

242295

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.556

High

1332384

RNF11
RING finger protein 11

1

0

High-throughput

0.556

High

1115562

ASPP2
Apoptosis-stimulating of p53 protein 2

1

1

High-throughput

0.555

High

341812

K2C75
Keratin, type II cytoskeletal 75

2

1

High-throughput

0.553

High

948359

KR122
Keratin-associated protein 12-2

2

4

High-throughput

0.553

High

1031007

K22O
Keratin, type II cytoskeletal 2 oral

2

1

High-throughput

0.553

High

1290544

ZN410
Zinc finger protein 410

2

1

High-throughput

0.553

High

1332366

KIFC3
Kinesin-like protein KIFC3

2

1

High-throughput

0.553

High

572077

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.523

High

950335

KR107
Keratin-associated protein 10-7

1

3

High-throughput

0.523

High

950832

KR109
Keratin-associated protein 10-9

1

3

High-throughput

0.523

High

1230144

K1C40
Keratin, type I cytoskeletal 40

1

1

High-throughput

0.523

High

159991

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

442404

GELS
Gelsolin

1

0

High-throughput

0.493

High

384701

CRYAB
Alpha-crystallin B chain

1

1

High-throughput

0.489

High

516694

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.481

High

1216228

H37
Histone H3-7

1

0

High-throughput

0.481

High

1258138

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.481

High

385979

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.470

High

415729

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.470

High

570507

GFAP
Glial fibrillary acidic protein

1

2

High-throughput

0.470

High

949938

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.439

High

1332368

BTBD2
BTB/POZ domain-containing protein 2

1

1

High-throughput

0.407

High

1332364

MDFI
MyoD family inhibitor

3

0

High-throughput

0.352

High

949666

KR124
Keratin-associated protein 12-4

3

0

High-throughput

0.352

High

1332374

GO45
Golgin-45

3

0

High-throughput

0.352

High

1160516

SMN
Survival motor neuron protein

3

0

High-throughput

0.344

High

1332383

TLR6
Toll-like receptor 6

2

0

High-throughput

0.328

High

1314591

IHO1
Interactor of HORMAD1 protein 1

2

0

High-throughput

0.327

High

70362

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

96955

P23D1
Proline-rich protein 23D1

2

0

High-throughput

0.316

High

124621

EYA2
Protein phosphatase EYA2

2

0

High-throughput

0.316

High

913889

ZN143
Zinc finger protein 143

2

0

High-throughput

0.316

High

1007956

PO6F2
POU domain, class 6, transcription factor 2

2

0

High-throughput

0.316

High

1063440

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

1095714

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

0

High-throughput

0.316

High

1130705

DIP2A
Disco-interacting protein 2 homolog A

2

0

High-throughput

0.316

High

1151779

RHOH
Rho-related GTP-binding protein RhoH

2

0

High-throughput

0.316

High

1244620

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.316

High

1286319

ANR23
Ankyrin repeat domain-containing protein 23

2

0

High-throughput

0.316

High

1332353

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

1332355

ZN526
Zinc finger protein 526

2

0

High-throughput

0.316

High

1332358

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

1332373

ALX4
Homeobox protein aristaless-like 4

2

0

High-throughput

0.316

High

1332376

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

0

High-throughput

0.316

High

1332377

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

0

High-throughput

0.316

High

1332380

LHX3
LIM/homeobox protein Lhx3

2

0

High-throughput

0.316

High

1332385

PKP3
Plakophilin-3

2

0

High-throughput

0.316

High

1332360

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

0

High-throughput

0.310

High

270105

TMCC2
Transmembrane and coiled-coil domains protein 2

2

0

High-throughput

0.300

High

848414

MAGA6
Melanoma-associated antigen 6

1

0

High-throughput

0.299

High

991627

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.299

High

1322112

SYCE1
Synaptonemal complex central element protein 1

1

0

High-throughput

0.299

High

564065

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

326739

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

754580

S10A3
Protein S100-A3

1

0

High-throughput

0.279

Low

902390

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

1

0

High-throughput

0.279

Low

1009681

NGAL
Neutrophil gelatinase-associated lipocalin

1

0

High-throughput

0.279

Low

1154326

CYTM
Cystatin-M

1

0

High-throughput

0.279

Low

1236022

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.279

Low

1286392

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.279

Low

1286437

DSG4
Desmoglein-4

1

0

High-throughput

0.279

Low

1332356

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.279

Low

1332357

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1332365

FSP1
Ferroptosis suppressor protein 1

1

0

High-throughput

0.279

Low

1332379

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.279

Low

1332382

SPB13
Serpin B13

1

0

High-throughput

0.279

Low

1332386

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

0

High-throughput

0.279

Low

160730

TOR1A
Torsin-1A

1

0

High-throughput

0.268

Low

167326

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.268

Low

246050

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

274666

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.268

Low

301568

WFS1
Wolframin

1

0

High-throughput

0.268

Low

374769

RASH
GTPase HRas

1

0

High-throughput

0.268

Low

650300

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

702480

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

896825

DYN2
Dynamin-2

1

0

High-throughput

0.268

Low

1279643

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1332354

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

0

High-throughput

0.268

Low

1332359

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1332363

COQA1
Collagen alpha-1(XXVI) chain

1

0

High-throughput

0.268

Low

352781

F107A
Actin-associated protein FAM107A

1

0

Small-scale

0.251

Low

167105

GEMI2
Gem-associated protein 2

1

0

High-throughput

0.232

Low

1332361

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

0

High-throughput

0.232

Low

1332371

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.232

Low

1332375

FA83D
Protein FAM83D

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025