HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.700

Property	Details
Experiments	12138209, 26238070, 32807901, 22103682
Identification Methods	affinity chromatography technology, pull down, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 710
+	Hs
		385994 P53_HUMAN (1-393): 0: 619: 100.00		PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55
+	Hs
		387500 P53_HUMAN (1-393): 0: 619: 100.00		PABP3_HUMAN (221-482): 6.38e-43: 166: 16.20
+	Hs
		386661 P53_HUMAN (1-393): 0: 619: 100.00		PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88