HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ROA2 (P22626)
Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
Gene: HNRNPA2B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32807901, 23443559
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 1 others more... GO:0016363 - nuclear matrix
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 353
+	Hs
		387274 P53_HUMAN (1-393): 0: 619: 100.00		MSI2H_HUMAN (1-341): 1.1e-55: 186: 27.57
+	Hs
		386661 P53_HUMAN (1-393): 0: 619: 100.00		PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67
+	Hs
		385994 P53_HUMAN (1-393): 0: 619: 100.00		PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95
+	Hs
		386711 P53_HUMAN (1-393): 0: 619: 100.00		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		385958 P53_HUMAN (1-393): 0: 619: 100.00		ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92
+	Hs
		1048224 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		852168 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		ROA3_HUMAN (3-103): 2.78e-17: 84: 33.66