HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ASPM (Q8IZT6)
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)
Gene: ASPM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32807901, 20308539
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 3477
+	Hs
		175893 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		ASPM_HUMAN (1-3477): 0: 2244: 100.00
+	Hs
		1224794 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		ASPM_HUMAN (1-3477): 0: 2244: 100.00
+	Hs
		386769 P53_HUMAN (1-393): 0: 619: 100.00		PLEC_HUMAN (1241-2615): 6.18e-30: 134: 10.29
+	Hs
		387576 P53_HUMAN (1-393): 0: 619: 100.00		MYO5C_HUMAN (2658-3307): 6.45e-23: 110: 10.82
+	Hs
		387710 P53_HUMAN (1-393): 0: 619: 100.00		MYH13_HUMAN (1939-3021): 7.39e-22: 107: 9.03
+	Hs
		387815 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (1887-3019): 6.85e-22: 107: 7.49
+	Hs
		387724 P53_HUMAN (1-393): 0: 619: 100.00		MYO5B_HUMAN (1256-1945): 6.28e-14: 81.1: 13.87
+	Hs
		386541 P53_HUMAN (1-393): 0: 619: 100.00		SPTB2_HUMAN (2326-3469): 1.32e-10: 70.2: 8.55
+	Hs
		70641 P53_HUMAN (1-393): 0: 619: 100.00		MYO9A_HUMAN (2899-3171): 1.6e-09: 66.4: 19.15
+	Dm
		1341764 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		ASP_DROME (2036-2741): 4.95e-16: 87.9: 15.76