Protein: ACT5
Actin-87E (EC 3.6.4.-)

Gene: ACT5, Act87E
Organism: Drosophila melanogaster
Interactions: 64
UniProt ID: P10981

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0015629 - actin cytoskeleton
GO:0016787 - hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

387021

ACT4
Actin, larval muscle

3

18

High-throughput

0.827

High

534380

Q9VPX6
Adenylyl cyclase-associated protein

3

20

High-throughput

0.827

High

386967

ACT2
Actin-42A

2

18

High-throughput

0.767

High

534352

ACT6
Actin, indirect flight muscle

2

19

High-throughput

0.767

High

534349

CADF
Cofilin/actin-depolymerizing factor homolog

1

20

High-throughput

0.656

High

534387

Q9VWR1
IP04855p

1

20

High-throughput

0.656

High

534342

SPTCA
Spectrin alpha chain

1

20

Small-scale

0.618

High

534375

RUVB1
RuvB-like helicase 1

1

8

Small-scale

0.618

High

432163

MYSA
Myosin heavy chain, muscle

1

13

High-throughput

0.575

High

534341

ACT1
Actin-5C

1

18

High-throughput

0.575

High

534379

GRCR1
Glutaredoxin domain-containing cysteine-rich protein CG31559

2

6

High-throughput

0.542

High

534392

GRCR2
Glutaredoxin domain-containing cysteine-rich protein CG12206

2

6

High-throughput

0.542

High

446258

MLC1
Myosin light chain alkali

1

3

High-throughput

0.514

High

482721

TPM2
Tropomyosin-2

1

15

High-throughput

0.514

High

534344

ACTN
Alpha-actinin, sarcomeric

1

17

High-throughput

0.514

High

534347

TNNI
Troponin I

1

2

High-throughput

0.514

High

534353

CPN
Calphotin

1

10

High-throughput

0.508

High

534354

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.508

High

534343

REF2P
Protein ref(2)P

1

0

High-throughput

0.486

High

534366

Q8T0T2
GH09296p

1

5

Small-scale

0.479

High

534371

ANLN
Anillin

1

10

Small-scale

0.479

High

195837

TAP
Basic helix-loop-helix neural transcription factor TAP

1

3

High-throughput

0.464

High

534373

Q9VB22
LD33695p

1

2

High-throughput

0.464

High

534369

Q962S2
60S ribosomal protein L41

1

0

High-throughput

0.460

High

534345

MLR
Myosin regulatory light chain 2

1

6

High-throughput

0.445

High

534346

MYSP2
Paramyosin, short form

1

16

High-throughput

0.445

High

534348

GSTS1
Glutathione S-transferase S1

1

3

High-throughput

0.445

High

534350

KARG
Arginine kinase 1

1

3

High-throughput

0.445

High

534377

Q9VM18
Trehalose 6-phosphate phosphatase

1

1

High-throughput

0.445

High

534367

Q8T3H9
AT04280p

1

1

High-throughput

0.439

High

534362

LASP1
LIM and SH3 domain protein Lasp

1

20

Small-scale

0.437

High

534388

PGPLE
Peptidoglycan-recognition protein LE

1

5

High-throughput

0.437

High

534390

Q9VYT3
FI23714p1

1

1

Small-scale

0.437

High

534360

SCARF
Inactive serine protease scarface

1

0

High-throughput

0.426

High

534378

Q9VNC4
Uncharacterized protein, isoform B

1

3

High-throughput

0.417

High

68039

A8DRW0
Cuticular protein 49Aa

1

9

High-throughput

0.407

High

72496

A9UNB7
ribose-5-phosphate isomerase

1

1

High-throughput

0.407

High

94194

D5SHN8
RT07823p

1

10

High-throughput

0.407

High

232044

WBL
Protein windbeutel

1

2

High-throughput

0.407

High

358455

ADH
Alcohol dehydrogenase

1

3

High-throughput

0.407

High

459974

ALF
Fructose-bisphosphate aldolase

1

3

High-throughput

0.407

High

534355

Q5U126
GEO11286p1

1

9

High-throughput

0.407

High

534356

Q6IHY5
Cytochrome c oxidase subunit 7A-like 2, isoform A

1

1

High-throughput

0.407

High

534357

Q7JUS9
Phosphate carrier protein, mitochondrial

1

4

High-throughput

0.407

High

534358

Q7K0W4
LD27203p

1

6

High-throughput

0.407

High

534359

Q7K2P1
Cuticular protein 50Cb

1

9

High-throughput

0.407

High

534361

Q8I062
GH23305p

1

1

High-throughput

0.407

High

534363

Q8MSI2
GH15296p

1

1

High-throughput

0.407

High

534365

Q8SZM2
RH04334p

1

2

High-throughput

0.407

High

534368

Q95RB2
Cuticular protein 49Ae

1

8

High-throughput

0.407

High

534370

Q9I7Q5
Cuticular protein 65Au, isoform A

1

4

High-throughput

0.407

High

534376

Q9VKE2
Crystallin, isoform A

1

20

High-throughput

0.407

High

534381

Q9VSN3
Cuticular protein 66D

1

10

High-throughput

0.407

High

534385

Q9VV46
Cuticular protein 72Ec

1

10

High-throughput

0.407

High

534389

Q9VYI1
Protein YIPF

1

1

High-throughput

0.407

High

534383

Q9VV20
Uncharacterized protein

1

0

High-throughput

0.265

Low

534386

Q9VVC2
Uncharacterized protein

1

0

High-throughput

0.265

Low

534351

MBN
Protein lethal(3)malignant blood neoplasm 1

1

0

High-throughput

0.232

Low

534364

Q8MT78
LD24677p

1

0

High-throughput

0.232

Low

534372

Q9V9U0
RE35358p

1

0

High-throughput

0.232

Low

534374

Q9VB86
LP07342p

1

0

High-throughput

0.232

Low

534382

Q9VSY0
Cuticular protein 67B

1

0

High-throughput

0.232

Low

534384

RETIN
Retinin

1

0

High-throughput

0.232

Low

534391

Q9W1F8
GEO08248p1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025