HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ZBTB2 (Q8N680)
Zinc finger and BTB domain-containing protein 2
Gene: ZBTB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	33301849, 19380588
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 514
+	Hs
		387152 P53_HUMAN (1-393): 0: 619: 100.00		ZN420_HUMAN (76-490): 8.55e-162: 477: 15.33
+	Hs
		387691 P53_HUMAN (1-393): 0: 619: 100.00		ZN180_HUMAN (66-451): 1e-136: 412: 17.09
+	Hs
		387019 P53_HUMAN (1-393): 0: 619: 100.00		ZN329_HUMAN (243-337): 5.51e-31: 128: 22.45
+	Hs
		387667 P53_HUMAN (1-393): 0: 619: 100.00		ZN629_HUMAN (68-331): 4.55e-21: 99.1: 7.74
+	Hs
		386642 P53_HUMAN (1-393): 0: 619: 100.00		ZBT17_HUMAN (1-208): 8.25e-14: 76.3: 30.88
+	Hs
		386574 P53_HUMAN (1-393): 0: 619: 100.00		ZNF92_HUMAN (77-185): 1.1e-12: 72.2: 6.20
+	Hs
		387020 P53_HUMAN (1-393): 0: 619: 100.00		ZN546_HUMAN (254-466): 4.63e-09: 61.2: 23.29