Protein: ARNT2
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1)

Gene: ARNT2
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9HBZ2

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 - response to hypoxia

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1122914

SIM2
Single-minded homolog 2

4

20

Small-scale

0.909

High

1161409

HIF1A
Hypoxia-inducible factor 1-alpha

3

19

High-throughput

0.875

High

1406994

NPAS1
Neuronal PAS domain-containing protein 1

3

18

High-throughput

0.855

High

1010419

SIM1
Single-minded homolog 1

3

20

Small-scale

0.849

High

1312147

NPAS3
Neuronal PAS domain-containing protein 3

2

18

High-throughput

0.817

High

1407420

EPAS1
Endothelial PAS domain-containing protein 1

2

19

Small-scale

0.793

High

681930

RBTN2
Rhombotin-2

2

2

High-throughput

0.783

High

965517

LMO4
LIM domain transcription factor LMO4

2

2

High-throughput

0.783

High

1307723

NPAS4
Neuronal PAS domain-containing protein 4

2

19

Small-scale

0.757

High

1407029

NPAS2
Neuronal PAS domain-containing protein 2

1

19

High-throughput

0.698

High

1438509

NCOA3
Nuclear receptor coactivator 3

1

20

High-throughput

0.698

High

1414781

TRAF4
TNF receptor-associated factor 4

3

15

High-throughput

0.678

High

1289310

DTX2
Probable E3 ubiquitin-protein ligase DTX2

3

2

High-throughput

0.667

High

777325

AHR
Aryl hydrocarbon receptor

1

20

Small-scale

0.647

High

894178

MEOX2
Homeobox protein MOX-2

1

6

High-throughput

0.621

High

1151660

TRIP6
Thyroid receptor-interacting protein 6

1

1

High-throughput

0.621

High

291866

STK16
Serine/threonine-protein kinase 16

2

3

High-throughput

0.606

High

633797

PSB1
Proteasome subunit beta type-1

2

4

High-throughput

0.606

High

1438510

CAN7
Calpain-7

2

1

High-throughput

0.606

High

881684

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

2

0

High-throughput

0.602

High

1438511

X5D985
Neuronal PAS domain-containing protein 3

1

20

High-throughput

0.590

High

1438514

X5DR67
Neuronal PAS domain-containing protein 3

1

20

High-throughput

0.590

High

1239788

FAP20
Fanconi anemia core complex-associated protein 20

2

0

High-throughput

0.580

High

1438507

MAGD1
Melanoma-associated antigen D1

1

14

Small-scale

0.561

High

1417310

AP1M1
AP-1 complex subunit mu-1

2

1

High-throughput

0.553

High

1438506

AP3M1
AP-3 complex subunit mu-1

2

1

High-throughput

0.553

High

180598

PLS1
Phospholipid scramblase 1

1

2

High-throughput

0.541

High

250342

VINEX
Vinexin

1

1

High-throughput

0.541

High

283551

TAD2A
Transcriptional adapter 2-alpha

1

10

High-throughput

0.541

High

572224

TRI27
Zinc finger protein RFP

1

3

High-throughput

0.541

High

783419

TRI23
E3 ubiquitin-protein ligase TRIM23

1

3

High-throughput

0.541

High

848351

MAGA4
Melanoma-associated antigen 4

1

14

High-throughput

0.541

High

1033429

CDR2
Cerebellar degeneration-related protein 2

1

1

High-throughput

0.541

High

1049005

REL
Proto-oncogene c-Rel

1

11

High-throughput

0.541

High

1090930

TRAF2
TNF receptor-associated factor 2

1

13

High-throughput

0.541

High

1093962

TRAF1
TNF receptor-associated factor 1

1

10

High-throughput

0.541

High

1095808

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

15

High-throughput

0.541

High

1120877

DGCR6
Protein DGCR6

1

1

High-throughput

0.541

High

1205995

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

13

High-throughput

0.541

High

1218017

MYOME
Myomegalin

1

11

High-throughput

0.541

High

1301011

RFX6
DNA-binding protein RFX6

1

2

High-throughput

0.541

High

1398361

CEP63
Centrosomal protein of 63 kDa

1

9

High-throughput

0.541

High

1401169

SPAG5
Sperm-associated antigen 5

1

12

High-throughput

0.541

High

1408394

SH3G2
Endophilin-A1

1

2

High-throughput

0.541

High

1416423

SSBP3
Single-stranded DNA-binding protein 3

1

1

High-throughput

0.541

High

1418865

ZN341
Zinc finger protein 341

1

1

High-throughput

0.541

High

1438501

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.541

High

1438502

RIM3A
RIMS-binding protein 3A

1

8

High-throughput

0.541

High

1438504

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.541

High

1438505

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.541

High

1438508

TACC3
Transforming acidic coiled-coil-containing protein 3

1

20

High-throughput

0.541

High

692810

CALL3
Calmodulin-like protein 3

1

1

High-throughput

0.536

High

832806

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.536

High

1107485

BIRC2
Baculoviral IAP repeat-containing protein 2

1

3

High-throughput

0.536

High

163474

MEIS2
Homeobox protein Meis2

1

0

High-throughput

0.518

High

167530

TX1B3
Tax1-binding protein 3

1

0

High-throughput

0.518

High

1103389

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.518

High

1350363

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.518

High

881742

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.513

High

1371704

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.508

High

423214

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

1063627

GOGA2
Golgin subfamily A member 2

1

10

High-throughput

0.494

High

1238608

RINT1
RAD50-interacting protein 1

1

1

High-throughput

0.494

High

1311477

TRI42
Tripartite motif-containing protein 42

1

12

High-throughput

0.494

High

1322146

SYCE1
Synaptonemal complex central element protein 1

1

1

High-throughput

0.494

High

1323353

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

1

High-throughput

0.494

High

1330086

USBP1
Harmonin-binding protein USHBP1

1

10

High-throughput

0.494

High

1411310

LZTS2
Leucine zipper putative tumor suppressor 2

1

12

High-throughput

0.494

High

1415233

KIFC3
Kinesin-like protein KIFC3

1

2

High-throughput

0.494

High

1418801

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

4

High-throughput

0.494

High

1162562

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

High-throughput

0.489

High

323571

TRI37
E3 ubiquitin-protein ligase TRIM37

1

7

High-throughput

0.481

High

326869

RIMB1
Peripheral-type benzodiazepine receptor-associated protein 1

1

13

High-throughput

0.481

High

1315787

CE57L
Centrosomal protein CEP57L1

1

1

High-throughput

0.481

High

143271

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

474306

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

1088034

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1133676

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

706319

S10A2
Protein S100-A2

1

5

High-throughput

0.470

High

116776

I3L3G9
NudE neurodevelopment protein 1

1

7

High-throughput

0.457

High

1438513

X5DP35
NudE neurodevelopment protein 1 isoform A

1

7

High-throughput

0.457

High

1250321

ATL4
ADAMTS-like protein 4

1

1

High-throughput

0.439

High

1438500

NDE1
Nuclear distribution protein nudE homolog 1

1

11

High-throughput

0.439

High

1241876

Q6P2R3
C6orf182 protein

1

1

High-throughput

0.417

High

1438512

X5DP20
DiGeorge syndrome critical region 6 isoform D

1

1

High-throughput

0.417

High

1438503

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.316

High

1328405

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.282

High

1359114

DYDC1
DPY30 domain-containing protein 1

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025