Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: B2CL2 (Q92843)
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)
Gene: BCL2L2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.792

The method score is based on:

Property Details
Experiments 25115399, 24491548
Identification Methods affinity chromatography technology, pull down, unspecified method
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~P53, BH4~P53
Common GO terms GO:0002931 - response to ischemia
GO:0005829 - cytosol
GO:0042981 - regulation of apoptotic process
GO:0043066 - negative regulation of apoptotic process
GO:0046982 - protein heterodimerization activity
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 393
Hs

1 193
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
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+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024