Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.771 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25283148, 23382381, 26238070, 24462112, 29795372, 29748603, 30067985, 30651545, 31647545, 32807901, 11923872, 34795231, 34591612, 20713061, 17268548, 21170034, 20816748, 22084066, 16474402, 26460617 and 15 others
more... |
| Identification Methods | affinity chromatography technology, pull down, unspecified method, proximity labelling technology, x-ray crystallography, enzymatic study, classical fluorescence spectroscopy, isothermal titration calorimetry, molecular sieving, nuclear magnetic resonance and 4 others
more... |
| Interaction Type | physical association, direct interaction, association, deubiquitination reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016605 - PML body and 2 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
