HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: S10AD (Q99584)
Protein S100-A13 (S100 calcium-binding protein A13)
Gene: S100A13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	S_100~TAD2
Common GO terms	GO:0005507 - copper ion binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm and 2 others more... GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 98
+	Hs
		387043 P53_HUMAN (1-393): 0: 619: 100.00		HORN_HUMAN (6-89): 2.99e-30: 114: 29.89
+	Hs
		386132 P53_HUMAN (1-393): 0: 619: 100.00		S100P_HUMAN (6-91): 5.62e-31: 106: 28.09
+	Hs
		386185 P53_HUMAN (1-393): 0: 619: 100.00		S10AB_HUMAN (6-91): 2.44e-30: 105: 35.96
+	Hs
		386104 P53_HUMAN (1-393): 0: 619: 100.00		S10A1_HUMAN (7-91): 2.29e-30: 104: 37.50
+	Hs
		386412 P53_HUMAN (1-393): 0: 619: 100.00		S10AA_HUMAN (6-98): 1.32e-29: 102: 26.04
+	Hs
		386865 P53_HUMAN (1-393): 0: 619: 100.00		FILA2_HUMAN (6-89): 3.52e-25: 99.5: 33.33
+	Hs
		380714 P53_HUMAN (1-393): 0: 619: 100.00		S100B_HUMAN (6-91): 3.01e-27: 96.8: 26.97
+	Hs
		386137 P53_HUMAN (1-393): 0: 619: 100.00		S10A4_HUMAN (8-91): 1.71e-26: 95.3: 32.18
+	Hs
		386155 P53_HUMAN (1-393): 0: 619: 100.00		S10A2_HUMAN (7-91): 3.32e-26: 94.5: 32.96
+	Hs
		386192 P53_HUMAN (1-393): 0: 619: 100.00		S10A3_HUMAN (8-91): 3.25e-25: 92.2: 28.74
+	Hs
		386512 P53_HUMAN (1-393): 0: 619: 100.00		S10AC_HUMAN (6-88): 3.59e-25: 91.8: 33.72
+	Hs
		385910 P53_HUMAN (1-393): 0: 619: 100.00		S10A8_HUMAN (6-98): 4.03e-25: 91.4: 23.66
+	Hs
		387288 P53_HUMAN (1-393): 0: 619: 100.00		S10AG_HUMAN (3-97): 7.39e-24: 88.7: 29.29
+	Hs
		385924 P53_HUMAN (1-393): 0: 619: 100.00		S10A6_HUMAN (8-91): 2.55e-23: 86.8: 31.77
+	Hs
		386191 P53_HUMAN (1-393): 0: 619: 100.00		S10A5_HUMAN (7-91): 8.22e-23: 85.6: 37.65