Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.55 0.642

The method score is based on:

Property Details
Experiments 27561390, 35131382, 38580884
Identification Methods affinity chromatography technology, enzymatic study, pull down, proximity labelling technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0070266 - necroptotic process
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024