Protein: FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)

Gene: FKB1A, FKBP1A
Organism: Homo sapiens
Interactions: 63
UniProt ID: P62942

Gene Ontology (top 5):
GO:0000413 - protein peptidyl-prolyl isomerization
GO:0003007 - heart morphogenesis
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005160 - transforming growth factor beta receptor binding
GO:0005527 - macrolide binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

787449

MTOR
Serine/threonine-protein kinase mTOR

16

8

Small-scale

0.984

High

738520

TGFR1
TGF-beta receptor type-1

6

7

Small-scale

0.944

High

601658

RYR1
Ryanodine receptor 1

4

10

Small-scale

0.893

High

738439

ACV1B
Activin receptor type-1B

2

7

Small-scale

0.805

High

923827

RYR3
Ryanodine receptor 3

2

9

Small-scale

0.778

High

923825

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

2

9

Small-scale

0.757

High

175665

TRI18
E3 ubiquitin-protein ligase Midline-1

2

10

High-throughput

0.754

High

383729

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

11

High-throughput

0.743

High

923826

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

9

High-throughput

0.743

High

923820

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

2

13

Small-scale

0.712

High

923835

GLMN
Glomulin

3

3

Small-scale

0.667

High

601874

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

9

High-throughput

0.665

High

431721

HS90A
Heat shock protein HSP 90-alpha

1

17

Small-scale

0.647

High

738325

BMR1A
Bone morphogenetic protein receptor type-1A

1

7

Small-scale

0.621

High

923822

ACVR1
Activin receptor type-1

1

7

Small-scale

0.618

High

923830

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

923834

RYR2
Ryanodine receptor 2

1

10

Small-scale

0.618

High

923838

Q9H4D1
Protein kinase

1

10

High-throughput

0.618

High

394495

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.611

High

496785

TAU
Microtubule-associated protein tau

2

5

Small-scale

0.585

High

779197

CCNF
Cyclin-F

2

2

High-throughput

0.584

High

923831

RPTOR
Regulatory-associated protein of mTOR

2

8

Small-scale

0.584

High

351343

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

2

1

Small-scale

0.584

High

883470

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

10

High-throughput

0.575

High

671636

PEBP1
Phosphatidylethanolamine-binding protein 1

2

2

High-throughput

0.571

High

923821

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.561

High

739522

ACVL1
Serine/threonine-protein kinase receptor R3

1

7

Small-scale

0.555

High

923837

BARD1
BRCA1-associated RING domain protein 1

1

12

High-throughput

0.552

High

923845

AHSP
Alpha-hemoglobin-stabilizing protein

1

0

High-throughput

0.549

High

167347

SMAD7
Mothers against decapentaplegic homolog 7

1

1

Small-scale

0.543

High

923836

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.536

High

806800

RS9
Small ribosomal subunit protein uS4

1

2

High-throughput

0.515

High

330657

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.513

High

923832

DCA11
DDB1- and CUL4-associated factor 11

1

4

Small-scale

0.512

High

335250

DYR
Dihydrofolate reductase

1

1

Small-scale

0.501

High

893877

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.501

High

923844

NLGN3
Neuroligin-3

1

0

Small-scale

0.486

High

923843

ABI2
Abl interactor 2

1

2

High-throughput

0.481

High

216208

CALU
Calumenin

1

4

High-throughput

0.479

High

244250

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

505615

EPB41
Protein 4.1

1

1

High-throughput

0.479

High

714812

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

High-throughput

0.479

High

724211

MSX2
Homeobox protein MSX-2

1

2

High-throughput

0.479

High

832334

MCM2
DNA replication licensing factor MCM2

1

8

High-throughput

0.479

High

923823

TRPC3
Short transient receptor potential channel 3

1

12

Small-scale

0.479

High

923824

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

1

High-throughput

0.479

High

923833

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

923840

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

Small-scale

0.479

High

923841

TRPC7
Short transient receptor potential channel 7

1

12

Small-scale

0.479

High

923846

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

923847

TRPC6
Short transient receptor potential channel 6

1

18

Small-scale

0.479

High

324324

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

771892

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

206952

SMAD6
Mothers against decapentaplegic homolog 6

1

1

Small-scale

0.457

High

632681

TYY1
Transcriptional repressor protein YY1

1

4

Small-scale

0.439

High

923828

SF3B4
Splicing factor 3B subunit 4

1

2

High-throughput

0.439

High

650908

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

720192

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

923848

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

923839

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

923842

DCA16
DDB1- and CUL4-associated factor 16

1

0

Small-scale

0.249

Low

923829

SHLD3
Shieldin complex subunit 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024