Protein: APOA2
Apolipoprotein A-II (Apo-AII) (ApoA-II) (Apolipoprotein A2) [Cleaved into: Proapolipoprotein A-II (ProapoA-II); Truncated apolipoprotein A-II (Apolipoprotein A-II(1-76))]

Gene: APOA2
Organism: Homo sapiens
Interactions: 103
UniProt ID: P02652

Gene Ontology (top 5):
GO:0002719 - negative regulation of cytokine production involved in immune response
GO:0005102 - signaling receptor binding
GO:0005319 - lipid transporter activity
GO:0005543 - phospholipid binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

387182

APOA1
Apolipoprotein A-I

4

1

Small-scale

0.676

High

230236

CREB3
Cyclic AMP-responsive element-binding protein 3

3

0

High-throughput

0.630

High

387539

GDPD1
Lysophospholipase D GDPD1

3

1

High-throughput

0.609

High

387500

APOD
Apolipoprotein D

3

0

Small-scale

0.597

High

129841

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.580

High

387506

MUC1
Mucin-1

2

0

High-throughput

0.580

High

387508

STOM
Stomatin

2

0

High-throughput

0.580

High

387521

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.580

High

387533

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.580

High

387552

PANX1
Pannexin-1

2

0

High-throughput

0.580

High

387561

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

0

High-throughput

0.580

High

387495

APOC2
Apolipoprotein C-II

2

0

High-throughput

0.559

High

387540

PCYXL
Prenylcysteine oxidase 1-like

1

1

High-throughput

0.536

High

387573

PCYOX
Prenylcysteine oxidase 1

1

1

High-throughput

0.536

High

387517

PLTP
Phospholipid transfer protein

1

0

Small-scale

0.527

High

132973

MATN2
Matrilin-2

1

0

High-throughput

0.513

High

175295

PLXB2
Plexin-B2

1

0

High-throughput

0.513

High

183116

GNPAT
Dihydroxyacetone phosphate acyltransferase

1

0

High-throughput

0.513

High

210655

KLK10
Kallikrein-10

1

0

High-throughput

0.513

High

351636

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.513

High

387497

ALBU
Albumin

1

0

High-throughput

0.513

High

387501

JUN
Transcription factor Jun

1

0

High-throughput

0.513

High

387504

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

387518

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

387541

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.513

High

387551

SNX27
Sorting nexin-27

1

0

High-throughput

0.513

High

387558

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

387560

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.513

High

387570

GDE1
Glycerophosphodiester phosphodiesterase 1

1

1

High-throughput

0.489

High

387534

ABCAD
ATP-binding cassette sub-family A member 13

1

0

Small-scale

0.480

High

387544

SCRB1
Scavenger receptor class B member 1

1

0

Small-scale

0.480

High

387546

NDRG1
Protein NDRG1

1

0

Small-scale

0.480

High

387569

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

Small-scale

0.480

High

387348

APOE
Apolipoprotein E

1

1

High-throughput

0.479

High

387502

SAA1
Serum amyloid A-1 protein

1

2

High-throughput

0.479

High

387503

SAA2
Serum amyloid A-2 protein

1

2

High-throughput

0.479

High

387511

SAA4
Serum amyloid A-4 protein

1

2

High-throughput

0.479

High

385345

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

387527

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.460

High

387555

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

387494

APOC1
Apolipoprotein C-I

1

0

High-throughput

0.458

High

387496

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.458

High

387498

TRFE
Serotransferrin

1

0

High-throughput

0.458

High

387507

FLNA
Filamin-A

1

0

High-throughput

0.458

High

387512

BASI
Basigin

1

0

High-throughput

0.458

High

387520

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

387525

K2C72
Keratin, type II cytoskeletal 72

1

0

High-throughput

0.458

High

387531

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

387543

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

387547

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

387548

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.458

High

387557

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

387576

RNF11
RING finger protein 11

1

0

Small-scale

0.458

High

239518

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.437

High

387526

MED1
Mediator of RNA polymerase II transcription subunit 1

1

1

High-throughput

0.437

High

387532

ASXL2
Putative Polycomb group protein ASXL2

1

3

High-throughput

0.437

High

387536

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.437

High

387559

ASXL3
Putative Polycomb group protein ASXL3

1

3

High-throughput

0.437

High

296899

DGAT1
Diacylglycerol O-acyltransferase 1

1

0

Small-scale

0.426

High

387499

LCAT
Phosphatidylcholine-sterol acyltransferase

1

0

Small-scale

0.426

High

387505

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

387515

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.426

High

387519

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.426

High

387524

APOF
Apolipoprotein F

1

0

Small-scale

0.426

High

387542

CTSR1
Cation channel sperm-associated protein 1

4

0

High-throughput

0.368

High

387509

CTR1
High affinity cationic amino acid transporter 1

2

0

High-throughput

0.316

High

387513

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

0

High-throughput

0.316

High

387514

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.316

High

387523

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

387545

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

387554

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.316

High

387568

TM45A
Transmembrane protein 45A

2

0

High-throughput

0.316

High

61077

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.279

Low

215481

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.279

Low

219793

CHSTA
Carbohydrate sulfotransferase 10

1

0

High-throughput

0.279

Low

387510

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

387522

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.279

Low

387528

MBRL
Membralin

1

0

High-throughput

0.279

Low

387529

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

0

High-throughput

0.279

Low

387530

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.279

Low

387535

CIR1
Corepressor interacting with RBPJ 1

1

0

High-throughput

0.279

Low

387537

ELMD2
ELMO domain-containing protein 2

1

0

High-throughput

0.279

Low

387538

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.279

Low

387553

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

387563

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.279

Low

387565

TM39A
Transmembrane protein 39A

1

0

High-throughput

0.279

Low

387572

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.279

Low

387574

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

387575

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low

49549

TMM82
Transmembrane protein 82

1

0

High-throughput

0.251

Low

48891

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.249

Low

219464

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.249

Low

287751

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.249

Low

387516

CNN1
Calponin-1

1

0

High-throughput

0.249

Low

387549

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.249

Low

387550

MED30
Mediator of RNA polymerase II transcription subunit 30

1

0

High-throughput

0.249

Low

387556

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.249

Low

387562

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.249

Low

387564

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

387566

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.249

Low

387567

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.249

Low

387571

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.249

Low

387577

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025