HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: JIP3 (Q9UPT6)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)
Gene: MAPK8IP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31152661
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0043066 - negative regulation of apoptotic process GO:0050821 - protein stabilization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1336
+	Hs
		229616 P53_HUMAN (1-393): 0: 619: 100.00		JIP4_HUMAN (6-1336): 0: 671: 54.25
+	Hs
		387328 P53_HUMAN (1-393): 0: 619: 100.00		ARHGH_HUMAN (375-1331): 4.89e-152: 508: 20.28
+	Hs
		386676 P53_HUMAN (1-393): 0: 619: 100.00		ROCK1_HUMAN (2-581): 2.57e-21: 103: 9.37
+	Hs
		386212 P53_HUMAN (1-393): 0: 619: 100.00		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		148271 P53_HUMAN (1-393): 0: 619: 100.00		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		386037 P53_HUMAN (1-393): 0: 619: 100.00		DESP_HUMAN (27-706): 3.94e-16: 86.8: 11.43