Protein: ASB6
Ankyrin repeat and SOCS box protein 6 (ASB-6)

Gene: ASB6
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q9NWX5

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1371881

CUL5
Cullin-5

7

17

Small-scale

0.966

High

1147139

ELOC
Elongin-C

4

3

Small-scale

0.894

High

1326646

KIF2B
Kinesin-like protein KIF2B

2

6

High-throughput

0.811

High

154443

SH2B2
SH2B adapter protein 2

2

15

High-throughput

0.783

High

407722

S100B
Protein S100-B

2

4

High-throughput

0.776

High

1434412

RNF41
E3 ubiquitin-protein ligase NRDP1

9

6

Small-scale

0.759

High

1451554

RBX2
RING-box protein 2

5

4

Small-scale

0.714

High

74372

ZBT42
Zinc finger and BTB domain-containing protein 42

2

7

High-throughput

0.700

High

1451400

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

4

13

High-throughput

0.699

High

316326

RECQ5
ATP-dependent DNA helicase Q5

1

5

High-throughput

0.691

High

1115460

CUL4B
Cullin-4B

1

17

High-throughput

0.691

High

1366043

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

19

High-throughput

0.691

High

1147294

ELOB
Elongin-B

4

3

High-throughput

0.683

High

1370406

CSN5
COP9 signalosome complex subunit 5

3

2

High-throughput

0.667

High

364184

MOS
Proto-oncogene serine/threonine-protein kinase mos

2

0

High-throughput

0.655

High

945170

CORO7
Coronin-7

2

6

High-throughput

0.628

High

1359644

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

10

High-throughput

0.618

High

1114448

CUL3
Cullin-3

1

17

High-throughput

0.618

High

1451560

ASB3
Ankyrin repeat and SOCS box protein 3

1

19

High-throughput

0.618

High

335192

ARI2
E3 ubiquitin-protein ligase ARIH2

2

8

High-throughput

0.611

High

185117

TELT
Telethonin

2

1

High-throughput

0.606

High

478734

HXB5
Homeobox protein Hox-B5

2

20

High-throughput

0.606

High

1415389

DUS23
Dual specificity protein phosphatase 23

2

14

High-throughput

0.606

High

192873

RPB4
DNA-directed RNA polymerase II subunit RPB4

2

0

High-throughput

0.602

High

251478

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

2

0

High-throughput

0.602

High

897087

MAP2
Methionine aminopeptidase 2

2

0

High-throughput

0.602

High

1313066

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

0

High-throughput

0.602

High

1094425

CSN1
COP9 signalosome complex subunit 1

2

3

High-throughput

0.601

High

282789

E2F6
Transcription factor E2F6

2

1

High-throughput

0.574

High

1380978

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

1

High-throughput

0.574

High

1399368

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

2

High-throughput

0.574

High

1447089

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

2

High-throughput

0.574

High

1330242

ZN655
Zinc finger protein 655

2

1

High-throughput

0.553

High

1255801

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

958722

CSN2
COP9 signalosome complex subunit 2

1

3

High-throughput

0.536

High

959076

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.536

High

983990

RBX1
E3 ubiquitin-protein ligase RBX1

1

4

High-throughput

0.536

High

984308

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

6

High-throughput

0.536

High

1272573

CSN6
COP9 signalosome complex subunit 6

1

1

High-throughput

0.536

High

1357672

PHLA1
Pleckstrin homology-like domain family A member 1

1

5

High-throughput

0.536

High

1391962

DCNL1
DCN1-like protein 1

1

2

High-throughput

0.536

High

1420236

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1437200

CSN7B
COP9 signalosome complex subunit 7b

1

1

High-throughput

0.536

High

1451553

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

4

High-throughput

0.536

High

1451556

CSN7A
COP9 signalosome complex subunit 7a

1

1

High-throughput

0.536

High

1451558

CSN3
COP9 signalosome complex subunit 3

1

2

High-throughput

0.536

High

1451559

TBD2B
TBC1 domain family member 2B

1

3

High-throughput

0.536

High

1232033

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

2

2

High-throughput

0.533

High

1395252

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

2

High-throughput

0.523

High

621772

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.513

High

983722

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.513

High

1278854

DCXR
L-xylulose reductase

1

0

High-throughput

0.513

High

1311180

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.513

High

1413207

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.513

High

423312

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

896902

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

298630

RAD17
Cell cycle checkpoint protein RAD17

1

2

High-throughput

0.489

High

1415883

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.489

High

1450067

ABCF3
ATP-binding cassette sub-family F member 3

1

1

High-throughput

0.489

High

1311789

HOMEZ
Homeobox and leucine zipper protein Homez

1

3

High-throughput

0.481

High

243107

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

415895

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.479

High

461979

HS90A
Heat shock protein HSP 90-alpha

1

11

High-throughput

0.479

High

468850

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.479

High

171597

S27A2
Long-chain fatty acid transport protein 2

1

4

High-throughput

0.445

High

505984

MYZAP
Myocardial zonula adherens protein

1

5

High-throughput

0.445

High

387752

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

3

High-throughput

0.437

High

387907

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.437

High

388018

FIBG
Fibrinogen gamma chain

1

3

High-throughput

0.437

High

425058

ADT2
ADP/ATP translocase 2

1

4

High-throughput

0.437

High

696674

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

1154941

NEDD8
Ubiquitin-like protein NEDD8

1

0

High-throughput

0.426

High

506038

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

1

High-throughput

0.407

High

667483

RPB1
DNA-directed RNA polymerase II subunit RPB1

4

0

High-throughput

0.364

High

723121

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

High-throughput

0.328

High

912250

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

0

High-throughput

0.328

High

1310133

MGAP
MAX gene-associated protein

2

0

High-throughput

0.328

High

1451557

GPN3
GPN-loop GTPase 3

2

0

High-throughput

0.328

High

539748

ACHB
Acetylcholine receptor subunit beta

2

0

High-throughput

0.316

High

1402952

ZN587
Zinc finger protein 587

2

0

High-throughput

0.316

High

1416028

SYTM
Threonine--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

1317006

FAM9B
Protein FAM9B

1

0

High-throughput

0.299

High

787802

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.279

Low

976165

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.279

Low

1243247

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

1364834

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

1428888

CF062
Uncharacterized protein C6orf62

1

0

High-throughput

0.279

Low

1449781

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.279

Low

1451555

UXT
Protein UXT

1

0

High-throughput

0.279

Low

163598

TPP1
Tripeptidyl-peptidase 1

1

0

High-throughput

0.268

Low

192512

INSI1
Insulin-induced gene 1 protein

1

0

Small-scale

0.249

Low

1289219

CAPS2
Calcium-dependent secretion activator 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025