HitPredict

Interactor 1: GNAT1 (P04695)
Guanine nucleotide-binding protein G(t) subunit alpha-1 (Transducin alpha-1 chain)
Gene: GNAT1

Interactor 2: GBB1 (P62871)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Bos taurus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	14578377
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	G-alpha~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005834 - heterotrimeric G-protein complex GO:0097381 - photoreceptor disc membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 Bt			1 340
+	Hs
		921512 GNAI1_HUMAN (1-350): 5.4e-172: 484: 67.80		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Bt
		920924 GNAI1_BOVIN (1-350): 5.4e-172: 484: 67.80		GBB1_BOVIN (1-340): 7.02e-105: 312: 100.00
+	Hs
		920929 GNAI1_HUMAN (1-350): 5.4e-172: 484: 67.80		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		926713 GNAI1_HUMAN (1-350): 5.4e-172: 484: 67.80		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		391374 GNAI2_HUMAN (1-350): 1.2e-168: 475: 65.92		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		444706 GNAI3_HUMAN (1-350): 1.79e-168: 475: 64.97		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		391373 GNAI2_HUMAN (1-350): 1.2e-168: 475: 65.92		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		391465 GNAI2_HUMAN (1-350): 1.2e-168: 475: 65.92		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		444705 GNAI3_HUMAN (1-350): 1.79e-168: 475: 64.97		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		444791 GNAI3_HUMAN (1-350): 1.79e-168: 475: 64.97		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		391321 GNAI2_HUMAN (1-350): 1.2e-168: 475: 65.92		GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24
+	Hs
		444660 GNAI3_HUMAN (1-350): 1.79e-168: 475: 64.97		GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24
+	Hs
		451000 GNAO_HUMAN (1-350): 2.04e-165: 467: 61.97		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Ce
		567431 GNAO_CAEEL (1-350): 2.57e-161: 456: 58.03		GBB1_CAEEL (1-340): 7.67e-107: 317: 85.88
+	Mm
		579642 GNAO_MOUSE (1-350): 3.93e-163: 461: 61.13		GBB1_MOUSE (1-340): 7.02e-105: 312: 100.00
+	Dm
		592741 GNAI_DROME (1-350): 1.33e-158: 450: 60.28		GBB1_DROME (1-340): 1.54e-103: 309: 83.53
+	Dm
		558469 GNAO_DROME (1-350): 1.26e-157: 447: 57.18		GBB1_DROME (1-340): 1.54e-103: 309: 83.53
+	Hs
		560863 GNAQ_HUMAN (1-349): 4.02e-154: 438: 49.15		GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24
+	Hs
		391370 GNAI2_HUMAN (1-350): 1.2e-168: 475: 65.92		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		444702 GNAI3_HUMAN (1-350): 1.79e-168: 475: 64.97		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93