Protein: KCRB
Creatine kinase B-type (EC 2.7.3.2) (Brain creatine kinase) (B-CK) (Creatine kinase B chain) (Creatine phosphokinase B-type) (CPK-B)

Gene: KCRB, CKB
Organism: Homo sapiens
Interactions: 216
UniProt ID: P12277

Gene Ontology (top 5):
GO:0004111 - creatine kinase activity
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

519251

ASB9
Ankyrin repeat and SOCS box protein 9

16

5

Small-scale

0.988

High

417066

KCRM
Creatine kinase M-type

5

4

High-throughput

0.922

High

519114

KCRU
Creatine kinase U-type, mitochondrial

3

4

High-throughput

0.827

High

519188

CUL3
Cullin-3

3

3

High-throughput

0.660

High

226383

PRKN
E3 ubiquitin-protein ligase parkin

3

2

High-throughput

0.640

High

519183

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.622

High

519244

ASB12
Ankyrin repeat and SOCS box protein 12

1

7

High-throughput

0.618

High

519256

ASB16
Ankyrin repeat and SOCS box protein 16

1

7

High-throughput

0.618

High

519171

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

0

High-throughput

0.586

High

336337

SODC
Superoxide dismutase [Cu-Zn]

2

0

High-throughput

0.585

High

519148

MAP1B
Microtubule-associated protein 1B

2

3

High-throughput

0.584

High

519229

RHG24
Rho GTPase-activating protein 24

3

3

High-throughput

0.578

High

383568

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

2

High-throughput

0.576

High

519201

RHGBB
Inactive Rho GTPase-activating protein 11B

2

4

High-throughput

0.571

High

519237

DOCK8
Dedicator of cytokinesis protein 8

2

1

High-throughput

0.571

High

519145

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

496186

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.554

High

519200

ANR55
Ankyrin repeat domain-containing protein 55

1

3

High-throughput

0.553

High

312463

ARI2
E3 ubiquitin-protein ligase ARIH2

2

2

Small-scale

0.550

High

519129

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

519177

SOS2
Son of sevenless homolog 2

2

0

High-throughput

0.547

High

519230

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.547

High

128415

DNM1L
Dynamin-1-like protein

1

3

High-throughput

0.536

High

519133

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.536

High

519139

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

2

High-throughput

0.536

High

519149

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

High-throughput

0.536

High

519187

CUL1
Cullin-1

1

3

High-throughput

0.536

High

519194

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

2

High-throughput

0.536

High

519131

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.530

High

519255

DOCK7
Dedicator of cytokinesis protein 7

2

1

High-throughput

0.521

High

434124

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

4

High-throughput

0.515

High

170233

TIF1A
Transcription intermediary factor 1-alpha

1

0

High-throughput

0.513

High

359608

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.513

High

452594

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

519121

VDAC1
Voltage-dependent anion-selective channel protein 1

1

0

High-throughput

0.513

High

519141

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

519239

PPTC7
Protein phosphatase PTC7 homolog

1

0

High-throughput

0.513

High

519241

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

519259

ARI3A
AT-rich interactive domain-containing protein 3A

1

0

High-throughput

0.513

High

519162

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

Small-scale

0.508

High

519197

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.508

High

174586

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

519175

UBE3A
Ubiquitin-protein ligase E3A

1

2

Small-scale

0.501

High

519247

CUL5
Cullin-5

1

3

Small-scale

0.501

High

519120

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.493

High

519206

USPL1
SUMO-specific isopeptidase USPL1

1

0

High-throughput

0.493

High

519289

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.493

High

519143

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.486

High

519178

GOGA2
Golgin subfamily A member 2

1

1

Small-scale

0.481

High

129674

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

2

High-throughput

0.479

High

168719

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

1

Small-scale

0.479

High

225497

PCDH7
Protocadherin-7

1

1

High-throughput

0.479

High

294313

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

298105

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

325010

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

High-throughput

0.479

High

375859

ALDOA
Fructose-bisphosphate aldolase A

1

1

High-throughput

0.479

High

384181

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

417123

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

487085

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

519115

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

519117

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

519118

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

519122

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.479

High

519124

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.479

High

519132

CDC27
Cell division cycle protein 27 homolog

1

2

Small-scale

0.479

High

519134

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.479

High

519136

MSX2
Homeobox protein MSX-2

1

1

High-throughput

0.479

High

519140

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

1

Small-scale

0.479

High

519144

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

519150

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

519151

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

519159

RND3
Rho-related GTP-binding protein RhoE

1

1

High-throughput

0.479

High

519163

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

519166

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.479

High

519173

KMT2A
Histone-lysine N-methyltransferase 2A

1

2

High-throughput

0.479

High

519181

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.479

High

519184

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

519185

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

519199

DDR2
Discoidin domain-containing receptor 2

1

2

High-throughput

0.479

High

519204

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.479

High

519208

RHG17
Rho GTPase-activating protein 17

1

2

High-throughput

0.479

High

519212

RHGBA
Rho GTPase-activating protein 11A

1

4

High-throughput

0.479

High

519216

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

519217

CNTRL
Centriolin

1

1

High-throughput

0.479

High

519224

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

519234

UBP38
Ubiquitin carboxyl-terminal hydrolase 38

1

1

Small-scale

0.479

High

519240

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.479

High

519246

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

519253

BICD1
Protein bicaudal D homolog 1

1

1

High-throughput

0.479

High

519257

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

1

1

High-throughput

0.479

High

519260

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

519266

RHG39
Rho GTPase-activating protein 39

1

2

High-throughput

0.479

High

519270

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

519273

CENPJ
Centromere protein J

1

1

High-throughput

0.479

High

519280

HDAC6
Histone deacetylase 6

1

2

High-throughput

0.479

High

519283

ANC2
Anaphase-promoting complex subunit 2

1

3

High-throughput

0.479

High

519284

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

519286

HDAC5
Histone deacetylase 5

1

2

High-throughput

0.479

High

519290

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

519282

S12A6
Solute carrier family 12 member 6

1

0

Small-scale

0.473

High

70645

MYO9A
Unconventional myosin-IXa

1

0

High-throughput

0.458

High

118183

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

119127

LEG9
Galectin-9

1

0

High-throughput

0.458

High

123478

PGRC1
Membrane-associated progesterone receptor component 1

1

0

Small-scale

0.458

High

255469

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

344429

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.458

High

373610

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

414551

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.458

High

430024

PROF1
Profilin-1

1

0

High-throughput

0.458

High

519119

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.458

High

519123

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.458

High

519125

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.458

High

519127

CALR
Calreticulin

1

0

High-throughput

0.458

High

519128

TKT
Transketolase

1

0

High-throughput

0.458

High

519130

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.458

High

519142

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

519146

PERI
Peripherin

1

0

High-throughput

0.458

High

519152

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.458

High

519153

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

519155

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

519157

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

519158

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

519160

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

519161

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.458

High

519164

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

519165

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.458

High

519167

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

519168

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.458

High

519169

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

519170

VIGLN
Vigilin

1

0

High-throughput

0.458

High

519172

CAP1
Adenylyl cyclase-associated protein 1

1

0

High-throughput

0.458

High

519174

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.458

High

519179

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

519180

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

519182

TADBP
TAR DNA-binding protein 43

1

0

Small-scale

0.458

High

519186

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

519191

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

519193

CUL7
Cullin-7

1

0

High-throughput

0.458

High

519202

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

519203

MIDN
Midnolin

1

0

High-throughput

0.458

High

519209

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

519218

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.458

High

519219

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

519222

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.458

High

519226

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

519238

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

519245

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

519258

NECD
Necdin

1

0

High-throughput

0.458

High

519261

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

519264

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

519267

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

519275

NGB
Neuroglobin

1

0

High-throughput

0.458

High

519281

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

519287

FND3A
Fibronectin type-III domain-containing protein 3A

1

0

High-throughput

0.458

High

519288

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.458

High

173822

MK13
Mitogen-activated protein kinase 13

1

1

Small-scale

0.445

High

305932

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.445

High

401327

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

519156

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.445

High

519189

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.445

High

519210

PKHA7
Pleckstrin homology domain-containing family A member 7

1

3

High-throughput

0.445

High

519269

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

2

High-throughput

0.445

High

519248

TRI63
E3 ubiquitin-protein ligase TRIM63

1

4

High-throughput

0.439

High

519277

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

69718

FHAD1
Forkhead-associated domain-containing protein 1

1

1

High-throughput

0.437

High

315796

AGRL2
Adhesion G protein-coupled receptor L2

1

2

High-throughput

0.437

High

345804

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

519126

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

519135

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

519138

FUS
RNA-binding protein FUS

1

1

High-throughput

0.437

High

519190

RBM39
RNA-binding protein 39

1

1

High-throughput

0.437

High

519195

NONO
Non-POU domain-containing octamer-binding protein

1

2

High-throughput

0.437

High

519198

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

519205

RC3H1
Roquin-1

1

3

Small-scale

0.437

High

519213

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

519221

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.437

High

519225

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

519228

CNTRB
Centrobin

1

1

High-throughput

0.437

High

519231

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

1

Small-scale

0.437

High

519236

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.437

High

519271

WDR76
WD repeat-containing protein 76

1

2

High-throughput

0.437

High

519272

RC3H2
Roquin-2

1

5

Small-scale

0.437

High

519285

PRP19
Pre-mRNA-processing factor 19

1

1

Small-scale

0.437

High

519192

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

519252

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

99547

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

519154

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.282

High

519232

SERP2
Stress-associated endoplasmic reticulum protein 2

1

0

High-throughput

0.282

High

519250

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.282

High

519262

TINF2
TERF1-interacting nuclear factor 2

1

0

High-throughput

0.282

High

519278

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.282

High

519137

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

519147

RAD52
DNA repair protein RAD52 homolog

1

0

Small-scale

0.279

Low

519242

MIPT3
TRAF3-interacting protein 1

1

0

Small-scale

0.279

Low

519249

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.279

Low

519268

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

519116

ITF2
Transcription factor 4

1

0

High-throughput

0.261

Low

519176

PAX8
Paired box protein Pax-8

1

0

High-throughput

0.261

Low

519263

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.261

Low

302849

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

519207

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

519211

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.249

Low

519214

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

519215

KCTD9
BTB/POZ domain-containing protein KCTD9

1

0

High-throughput

0.249

Low

519220

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

519227

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

519233

CE120
Centrosomal protein of 120 kDa

1

0

High-throughput

0.249

Low

519235

POC1A
POC1 centriolar protein homolog A

1

0

High-throughput

0.249

Low

519243

DUS19
Dual specificity protein phosphatase 19

1

0

High-throughput

0.249

Low

519254

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

519265

SPEF2
Sperm flagellar protein 2

1

0

High-throughput

0.249

Low

519274

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.249

Low

519276

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.249

Low

519279

HSFX1
Heat shock transcription factor, X-linked

1

0

High-throughput

0.249

Low

519196

SF01
Splicing factor 1

1

0

High-throughput

0.232

Low

519223

LACC1
Purine nucleoside phosphorylase LACC1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024