HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32912968, 12897149
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 317
+	Hs
		388597 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		ANR44_HUMAN (3-219): 9.3e-39: 147: 18.50
+	Hs
		388725 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		358831 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		ANR44_HUMAN (3-219): 9.3e-39: 147: 18.50
+	Hs
		388207 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		ANK1_HUMAN (224-317): 3.18e-13: 72.5: 14.85
+	Hs
		388624 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		ANKR7_HUMAN (78-256): 1.01e-13: 71.6: 35.20