Interactor 1: AMBP (P02760)
Protein AMBP (Protein HC) [Cleaved into: Alpha-1-microglobulin (EC 1.6.2.-) (Alpha-1 microglycoprotein) (Complex-forming glycoprotein heterogeneous in charge); Inter-alpha-trypsin inhibitor light chain (ITI-LC) (Bikunin) (EDC1) (HI-30) (Uronic-acid-rich protein); Trypstatin]
Gene: AMBP

Interactor 2: ITIH1 (P19827)
Inter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP)
Gene: ITIH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 37343697
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0030246 - carbohydrate binding
GO:0070062 - extracellular exosome
GO:0072562 - blood microparticle
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 352
Hs

1 911
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025