Interactor 1: CY24B (P04839)
Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (NADPH oxidase 2) (Neutrophil cytochrome b 91 kDa polypeptide) (Superoxide-generating NADPH oxidase heavy chain subunit) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome)
Gene: CYBB

Interactor 2: CY24A (P13498)
Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox)
Gene: CYBA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 33961781, 36122532
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006801 - superoxide metabolic process
GO:0006954 - inflammatory response
GO:0020037 - heme binding
and 11 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 570
Hs

1 195
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024