Protein: FETUA
Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin) (Ba-alpha-2-glycoprotein) (Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B]

Gene: FETUA, AHSG
Organism: Homo sapiens
Interactions: 103
UniProt ID: P02765

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001503 - ossification
GO:0004866 - endopeptidase inhibitor activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

62879

POTEF
POTE ankyrin domain family member F

3

0

High-throughput

0.629

High

240443

PRKN
E3 ubiquitin-protein ligase parkin

3

0

High-throughput

0.613

High

389748

GDPD1
Lysophospholipase D GDPD1

3

1

High-throughput

0.609

High

389749

UBP38
Ubiquitin carboxyl-terminal hydrolase 38

3

1

High-throughput

0.609

High

389699

TAU
Microtubule-associated protein tau

2

1

High-throughput

0.601

High

389757

SNX27
Sorting nexin-27

2

1

High-throughput

0.574

High

389770

FBX2
F-box only protein 2

2

1

Small-scale

0.565

High

389719

CAV2
Caveolin-2

2

0

High-throughput

0.547

High

210664

KLK10
Kallikrein-10

1

3

High-throughput

0.536

High

389714

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.536

High

389736

KPCZ
Protein kinase C zeta type

1

1

High-throughput

0.536

High

389694

FYN
Tyrosine-protein kinase Fyn

2

1

High-throughput

0.521

High

389763

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

2

High-throughput

0.521

High

361044

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

389688

ALBU
Albumin

1

0

High-throughput

0.513

High

389707

LEG3
Galectin-3

1

0

High-throughput

0.513

High

389765

DDX31
ATP-dependent DNA helicase DDX31

1

0

High-throughput

0.513

High

389725

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.508

High

389729

GRB2
Growth factor receptor-bound protein 2

1

2

High-throughput

0.508

High

389693

INSR
Insulin receptor

1

6

Small-scale

0.501

High

389734

TIE2
Angiopoietin-1 receptor

1

3

High-throughput

0.500

High

389742

DDR2
Discoidin domain-containing receptor 2

1

6

High-throughput

0.500

High

180649

TIF1A
Transcription intermediary factor 1-alpha

1

2

High-throughput

0.489

High

193484

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

1

High-throughput

0.489

High

251690

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

1

High-throughput

0.489

High

290284

KS6A4
Ribosomal protein S6 kinase alpha-4

1

1

High-throughput

0.489

High

389705

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.489

High

389720

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

389731

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.489

High

389743

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

2

High-throughput

0.489

High

389745

STRAA
STE20-related kinase adapter protein alpha

1

1

High-throughput

0.489

High

389746

MYLK4
Myosin light chain kinase family member 4

1

2

High-throughput

0.489

High

389751

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.489

High

389768

PHF11
PHD finger protein 11

1

6

High-throughput

0.489

High

389769

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

1

High-throughput

0.489

High

389771

CD11A
Cyclin-dependent kinase 11A

1

1

High-throughput

0.489

High

389695

PGS2
Decorin

1

0

Small-scale

0.480

High

389696

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.480

High

362557

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.479

High

389724

RAC3
Ras-related C3 botulinum toxin substrate 3

1

1

High-throughput

0.479

High

389739

RHOH
Rho-related GTP-binding protein RhoH

1

2

High-throughput

0.479

High

389761

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.479

High

389762

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

389691

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

1

High-throughput

0.470

High

389760

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

377903

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

389689

CATA
Catalase

1

0

High-throughput

0.458

High

389697

FURIN
Furin

1

0

High-throughput

0.458

High

389700

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

389701

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

389703

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.458

High

389704

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

389706

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

389709

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

389710

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.458

High

389711

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

389712

CALX
Calnexin

1

0

High-throughput

0.458

High

389728

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

389730

H31
Histone H3.1

1

0

High-throughput

0.458

High

389735

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

389750

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

389773

LY96
Lymphocyte antigen 96

1

0

Small-scale

0.458

High

389744

STYK1
Tyrosine-protein kinase STYK1

1

5

High-throughput

0.457

High

389747

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

1

Small-scale

0.445

High

126280

TLR4
Toll-like receptor 4

1

2

Small-scale

0.437

High

277243

PITX3
Pituitary homeobox 3

1

2

Small-scale

0.437

High

302302

RNF8
E3 ubiquitin-protein ligase RNF8

1

2

High-throughput

0.437

High

318566

RHBT1
Rho-related BTB domain-containing protein 1

1

3

High-throughput

0.437

High

362112

ABL1
Tyrosine-protein kinase ABL1

1

1

High-throughput

0.437

High

389690

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

389692

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

7

High-throughput

0.437

High

389698

ARAF
Serine/threonine-protein kinase A-Raf

1

1

High-throughput

0.437

High

389708

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

High-throughput

0.437

High

389721

RND2
Rho-related GTP-binding protein RhoN

1

3

High-throughput

0.437

High

389722

EPHA4
Ephrin type-A receptor 4

1

7

High-throughput

0.437

High

389737

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.437

High

389752

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

389753

RND1
Rho-related GTP-binding protein Rho6

1

3

High-throughput

0.437

High

389754

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

389756

THOC3
THO complex subunit 3

1

1

Small-scale

0.437

High

389758

RANB9
Ran-binding protein 9

1

2

High-throughput

0.437

High

389759

KCD15
BTB/POZ domain-containing protein KCTD15

1

2

Small-scale

0.437

High

389764

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

389767

EPHA6
Ephrin type-A receptor 6

1

3

High-throughput

0.437

High

389772

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

0

High-throughput

0.426

High

389723

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

389741

MK06
Mitogen-activated protein kinase 6

2

0

High-throughput

0.328

High

389702

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.313

High

389738

DUS4
Dual specificity protein phosphatase 4

2

0

High-throughput

0.298

High

389755

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.292

High

389715

CAH8
Carbonic anhydrase-related protein

1

0

High-throughput

0.279

Low

389718

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.279

Low

389732

CDK5
Cyclin-dependent kinase 5

1

0

High-throughput

0.279

Low

352282

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.269

Low

293022

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

389716

ARL2
ADP-ribosylation factor-like protein 2

1

0

High-throughput

0.249

Low

389717

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

389726

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.249

Low

389727

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

389733

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.249

Low

389740

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

389766

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

389713

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025