HitPredict

Interactor 1: VDAC1 (P04840)
Mitochondrial outer membrane protein porin 1 (Voltage-dependent anion-selective channel protein 1) (VDAC-1)
Gene: POR1

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31399574, 37295430, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 283 Sc			1 705
+	Dm
		365467 VDAC_DROME (1-283): 5.88e-97: 288: 27.02		HSP83_DROME (3-705): 0: 999: 59.58
+	Sc
		365523 VDAC1_YEAST (1-283): 9.45e-90: 270: 100.00		HSP82_YEAST (1-705): 0: 968: 95.63
+	Ca
		804471 VDAC_CANAL (1-283): 6.82e-79: 242: 51.23		HSP90_CANAL (4-705): 0: 953: 82.36
+	Hs
		330625 TOM40_HUMAN (3-279): 8.2e-52: 175: 15.49		HS90A_HUMAN (4-705): 0: 1013: 60.67
+	Hs
		538100 VDAC1_HUMAN (3-283): 5.89e-99: 293: 24.38		ENPL_HUMAN (3-680): 0: 893: 47.10
+	Dm
		1277072 VDAC_DROME (1-283): 5.88e-97: 288: 27.02		Q9VAY2_DROME (3-676): 0: 833: 47.09