HitPredict

Interactor 1: GNAI2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI2

Interactor 2: GRDN (Q3V6T2)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: CCDC88A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1871
+	Hs
		444740 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		GRDN_HUMAN (1-1871): 2.19e-149: 509: 100.00
+	Hs
		391343 GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		724760 GNAI1_HUMAN (1-355): 8.33e-178: 498: 87.89		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		444802 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		DAPLE_HUMAN (862-1846): 6.94e-26: 119: 11.33
+	Hs
		451051 GNAO_HUMAN (1-355): 1.03e-173: 488: 69.30		MYH4_HUMAN (5-707): 1.9e-26: 121: 12.26
+	Hs
		724759 GNAS2_HUMAN (1-355): 1.94e-147: 423: 38.83		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		148655 GNAS2_HUMAN (1-355): 1.94e-147: 423: 38.83		CTRO_HUMAN (144-645): 2.42e-16: 88.1: 16.63