HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	27248496, 30021884
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031492 - nucleosomal DNA binding GO:0046982 - protein heterodimerization activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 421
+	Hs
		578452 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		578445 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		555286 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Sc
		392291 H2A2_YEAST (16-128): 1.02e-59: 181: 79.65		RCC1_YEAST (192-419): 1.22e-30: 124: 18.85
+	Sc
		392051 H2A1_YEAST (16-127): 9.92e-53: 164: 80.36		RCC1_YEAST (192-419): 1.22e-30: 124: 18.85