Protein: SEMG2
Semenogelin-2 (Semenogelin II) (SGII)

Gene: SEMG2
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q02383

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0008270 - zinc ion binding
GO:0019731 - antibacterial humoral response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1036600

DPOLL
DNA polymerase lambda

3

3

High-throughput

0.656

High

247836

NUPR1
Nuclear protein 1

2

1

High-throughput

0.628

High

391607

FRIH
Ferritin heavy chain

2

1

High-throughput

0.628

High

1036570

MSS51
Putative protein MSS51 homolog, mitochondrial

2

1

High-throughput

0.628

High

1036573

BSPRY
B box and SPRY domain-containing protein

2

2

High-throughput

0.628

High

1036601

S22AD
Solute carrier family 22 member 13

2

1

High-throughput

0.628

High

72872

HACD1
Very-long-chain

3

1

High-throughput

0.609

High

689816

CD27
CD27 antigen

3

1

High-throughput

0.609

High

1036589

LS14B
Protein LSM14 homolog B

3

1

High-throughput

0.609

High

999341

HBB
Hemoglobin subunit beta

2

0

High-throughput

0.602

High

1036594

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

0

High-throughput

0.602

High

1036568

CNGA3
Cyclic nucleotide-gated channel alpha-3

2

1

High-throughput

0.574

High

1036569

SYT16
Synaptotagmin-16

2

1

High-throughput

0.574

High

1036575

CI139
Putative uncharacterized protein LINC02908

2

1

High-throughput

0.574

High

407849

SEMG1
Semenogelin-1

2

0

Small-scale

0.559

High

136372

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

1

High-throughput

0.536

High

168228

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.536

High

214121

DHH
Desert hedgehog protein

1

1

High-throughput

0.536

High

317516

TPPP
Tubulin polymerization-promoting protein

1

1

High-throughput

0.536

High

420232

IFNW1
Interferon omega-1

1

1

High-throughput

0.536

High

939893

DLX6
Homeobox protein DLX-6

1

1

High-throughput

0.536

High

1036578

ZN550
Zinc finger protein 550

1

1

High-throughput

0.536

High

1036581

BHE23
Class E basic helix-loop-helix protein 23

1

1

High-throughput

0.536

High

1036587

KIF2C
Kinesin-like protein KIF2C

1

1

High-throughput

0.536

High

1036591

FOXP3
Forkhead box protein P3

1

1

High-throughput

0.536

High

1036597

MAT2B
Methionine adenosyltransferase 2 subunit beta

1

1

High-throughput

0.536

High

1036598

TXD16
Thioredoxin domain-containing protein 16

1

1

High-throughput

0.536

High

1036567

CDK10
Cyclin-dependent kinase 10

1

1

High-throughput

0.515

High

596746

DPEP1
Dipeptidase 1

1

0

High-throughput

0.513

High

692685

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.513

High

1036576

LIGO2
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2

1

0

High-throughput

0.513

High

1036599

TRI10
Tripartite motif-containing protein 10

1

0

High-throughput

0.513

High

66929

AQ12B
Putative aquaporin-12B

1

1

High-throughput

0.489

High

298846

LYZL6
Lysozyme-like protein 6

1

1

High-throughput

0.489

High

327044

NXPH3
Neurexophilin-3

1

1

High-throughput

0.489

High

1023754

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.489

High

1036565

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

1

High-throughput

0.489

High

1036566

SNTB2
Beta-2-syntrophin

1

1

High-throughput

0.489

High

1036577

OTOP1
Proton channel OTOP1

1

1

High-throughput

0.489

High

1036582

O13G1
Olfactory receptor 13G1

1

1

High-throughput

0.489

High

1036583

RDH11
Retinol dehydrogenase 11

1

1

High-throughput

0.489

High

1036586

TIMD4
T-cell immunoglobulin and mucin domain-containing protein 4

1

1

High-throughput

0.489

High

1036588

TM2D3
TM2 domain-containing protein 3

1

1

High-throughput

0.489

High

1036592

IF3M
Translation initiation factor IF-3, mitochondrial

1

1

High-throughput

0.489

High

1036593

RM46
Large ribosomal subunit protein mL46

1

1

High-throughput

0.489

High

1036596

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

1

High-throughput

0.489

High

522653

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

1

Small-scale

0.481

High

455642

KLK3
Prostate-specific antigen

1

2

High-throughput

0.479

High

465843

MSMB
Beta-microseminoprotein

1

1

High-throughput

0.479

High

534952

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.479

High

582568

PPAP
Prostatic acid phosphatase

1

1

High-throughput

0.479

High

671777

ZA2G
Zinc-alpha-2-glycoprotein

1

1

High-throughput

0.479

High

872223

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

908816

NEK2
Serine/threonine-protein kinase Nek2

1

1

Small-scale

0.479

High

1036590

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

537001

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

563643

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

892844

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

926952

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

395945

ESR1
Estrogen receptor

1

3

High-throughput

0.445

High

515880

SAA1
Serum amyloid A-1 protein

1

1

High-throughput

0.445

High

626186

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.445

High

969581

RS15A
Small ribosomal subunit protein uS8

1

1

High-throughput

0.445

High

1022838

EFNB1
Ephrin-B1

1

1

High-throughput

0.445

High

1036564

PPID
Peptidyl-prolyl cis-trans isomerase D

1

1

High-throughput

0.445

High

1036584

ESR2
Estrogen receptor beta

1

3

High-throughput

0.445

High

1036585

SEH1
Nucleoporin SEH1

1

1

High-throughput

0.437

High

244963

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

351680

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.426

High

1036595

CBLN4
Cerebellin-4

1

0

High-throughput

0.426

High

191959

TEX28
Testis-specific protein TEX28

1

1

High-throughput

0.407

High

733693

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

1

High-throughput

0.407

High

1036571

Q5JQP4
DNA polymerase

1

3

High-throughput

0.407

High

754564

S10A3
Protein S100-A3

2

0

High-throughput

0.328

High

1036572

CAHM4
Calcium homeostasis modulator protein 4

2

0

High-throughput

0.328

High

1036574

HPHL1
Ferroxidase HEPHL1

2

0

High-throughput

0.328

High

1036579

LYG2
Lysozyme g-like protein 2

2

0

High-throughput

0.328

High

516657

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

0

High-throughput

0.288

High

225998

STX6
Syntaxin-6

1

0

High-throughput

0.279

Low

1036580

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025