HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: RFC4 (P40339)
Replication factor C subunit 4 (Replication factor C4) (Activator 1 37 kDa subunit)
Gene: RFC4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006281 - DNA repair
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 132 Sc			1 323
+	Hs
		391575 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		RFC4_HUMAN (4-318): 3.24e-84: 259: 34.36
+	Hs
		391576 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		RFC2_HUMAN (7-318): 6.99e-84: 258: 60.19
+	Hs
		391584 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		RFC5_HUMAN (2-316): 6.89e-82: 253: 34.80
+	Sc
		392414 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		RFC3_YEAST (3-321): 1.39e-79: 247: 33.95
+	Sc
		392455 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		RFC2_YEAST (8-319): 8.31e-77: 240: 34.24
+	Hs
		391585 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		RFC3_HUMAN (10-322): 5.12e-64: 207: 22.61
+	Sc
		392410 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		RFC5_YEAST (10-317): 1.76e-57: 190: 22.13
+	Sc
		392415 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		RFC1_YEAST (11-227): 2.97e-15: 78.6: 26.72