Protein: MAD2
Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)

Gene: MAD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P40958

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0033597 - mitotic checkpoint complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

640848

CDC20
APC/C activator protein CDC20

14

8

Small-scale

0.984

High

778457

MAD1
Spindle assembly checkpoint component MAD1

7

1

Small-scale

0.974

High

778481

MAD2
Mitotic spindle checkpoint component MAD2

4

5

Small-scale

0.875

High

643041

BUB3
Cell cycle arrest protein BUB3

2

3

Small-scale

0.789

High

769945

WRIP1
DNA-dependent ATPase MGS1

1

2

High-throughput

0.656

High

778483

MAD3
Spindle assembly checkpoint component MAD3

3

7

Small-scale

0.650

High

778492

RRB1
Ribosome assembly protein RRB1

1

2

High-throughput

0.618

High

778482

BUB1
Checkpoint serine/threonine-protein kinase BUB1

2

8

Small-scale

0.595

High

578545

SEC18
Vesicular-fusion protein SEC18

1

1

High-throughput

0.587

High

342732

ENO1
Enolase 1

1

1

High-throughput

0.536

High

340695

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.513

High

411020

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.513

High

524344

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.513

High

611740

TRX2
Thioredoxin-2

1

0

High-throughput

0.513

High

657247

URA7
CTP synthase 1

1

0

High-throughput

0.513

High

778494

YO283
Broad-specificity phosphatase YOR283W

1

0

High-throughput

0.513

High

342948

ENO2
Enolase 2

1

1

High-throughput

0.489

High

605199

MSN1
Protein MSN1

1

0

High-throughput

0.486

High

755610

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.486

High

774329

POG1
Transcriptional activator POG1

1

0

High-throughput

0.486

High

778491

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.486

High

778496

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.486

High

699427

RAEP
Rab proteins geranylgeranyltransferase component A

1

0

Small-scale

0.480

High

687792

MSB2
Signaling mucin MSB2

1

4

High-throughput

0.464

High

778488

UFD2
E4 ubiquitin-protein ligase UFD2

1

0

High-throughput

0.460

High

778495

SCM3
Protein SCM3

1

0

High-throughput

0.460

High

778489

H3
Histone H3

1

1

Small-scale

0.457

High

511651

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

694882

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

778484

KEL2
Kelch repeat-containing protein 2

1

2

High-throughput

0.439

High

778487

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

751979

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

3

High-throughput

0.417

High

454914

CDC16
Anaphase-promoting complex subunit CDC16

1

8

Small-scale

0.408

High

778490

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.282

High

778497

YB296
Uncharacterized protein YBR296C-A

1

0

High-throughput

0.282

High

778493

AP1G1
AP-1 complex subunit gamma-1

1

0

High-throughput

0.279

Low

686850

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.265

Low

767578

NU157
Nucleoporin NUP157

1

0

High-throughput

0.265

Low

778485

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.265

Low

350887

YPT1
GTP-binding protein YPT1

1

0

Small-scale

0.261

Low

589536

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

0

Small-scale

0.261

Low

731584

EAP1
Protein EAP1

1

0

High-throughput

0.251

Low

762721

YJU6
Putative transcriptional regulatory protein YJL206C

1

0

High-throughput

0.251

Low

778486

YG5Q
Uncharacterized protein YGR273C

1

0

High-throughput

0.251

Low

662479

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024