HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: GCN5 (Q03330)
Histone acetyltransferase GCN5 (EC 2.3.1.48) (Histone crotonyltransferase GCN5) (EC 2.3.1.-)
Gene: GCN5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	9733731, 21734642, 21179020
Identification Methods	enzymatic study, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Sc			1 439
+	Hs
		1087073 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		KAT2B_HUMAN (2-430): 0: 527: 39.22
+	Hs
		391825 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		KAT2B_HUMAN (2-430): 0: 527: 39.22
+	Hs
		1087072 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Hs
		391824 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Hs
		998866 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		391671 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		998781 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Mm
		70932 H2A3_MOUSE (3-128): 9.58e-63: 189: 75.40		EP300_MOUSE (257-431): 4.09e-38: 149: 23.08
+	Hs
		244848 H2A1J_HUMAN (3-128): 1.79e-63: 191: 74.60		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		1067038 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		BRD3_HUMAN (303-435): 2.85e-36: 143: 30.44
+	Hs
		244634 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		244795 H2A1H_HUMAN (3-128): 3.42e-63: 190: 75.40		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		1066979 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		BRD3_HUMAN (303-435): 2.85e-36: 143: 30.44
+	Hs
		243783 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		631492 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		BRD2_HUMAN (279-436): 2.56e-34: 137: 26.25
+	Hs
		391554 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		BRD2_HUMAN (279-436): 2.56e-34: 137: 26.25
+	Hs
		1087035 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		PB1_HUMAN (289-437): 7.01e-17: 85.5: 15.48
+	Hs
		391768 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		PB1_HUMAN (289-437): 7.01e-17: 85.5: 15.48
+	Hs
		391923 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		BAZ1A_HUMAN (330-431): 9.38e-16: 82: 39.81
+	Sc
		392389 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		BDF1_YEAST (349-432): 9.45e-09: 59.7: 38.37