Interactor 1: AT1B1 (P05026)
Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)
Gene: ATP1B1

Interactor 2: ATP4A (P20648)
Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump)
Gene: ATP4A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 33961781, 17255364
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase_C~Na_K-ATPase
Common GO terms GO:0005391 - P-type sodium:potassium-exchanging transporter activity
GO:0005886 - plasma membrane
GO:0006883 - intracellular sodium ion homeostasis
GO:0016324 - apical plasma membrane
GO:0030007 - intracellular potassium ion homeostasis
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 303
Hs

1 1035
+ Ss
+ Hs
+ Mm
+ Oc
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Oc
+ Hs
+ Ss
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024