Interactor 1: LACI (P03023)
Lactose operon repressor
Gene: LACI

Interactor 2: LACI (P03023)
Lactose operon repressor
Gene: LACI

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 10700279, 19805348, 16858726
Identification Methods x-ray crystallography, cross-linking study, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LacI~LacI, LacI~Peripla_BP_3, Peripla_BP_3~Peripla_BP_3
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0003700 - DNA-binding transcription factor activity
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 360
Ec

1 360
+ Ec
+ Ec
+ Ec
+ Bs
+ Ec
+ Ec
+ Sp
+ Ec
+ Ec
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025