Interactor 1: IL1B (P10749)
Interleukin-1 beta (IL-1 beta)
Gene: IL1B

Interactor 2: CASP1 (P29452)
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Gene: CASP1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 25607459, 18725521
Identification Methods affinity chromatography technology, protease assay
Interaction Type physical association, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0007613 - memory
GO:0032496 - response to lipopolysaccharide
GO:0033198 - response to ATP
GO:0043065 - positive regulation of apoptotic process
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 269
Mm

1 402
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024