Interactor 1: IL5 (P05113)
Interleukin-5 (IL-5) (B-cell differentiation factor I) (Eosinophil differentiation factor) (T-cell replacing factor) (TRF)
Gene: IL5
Interactor 2: IL5RA (Q01344)
Interleukin-5 receptor subunit alpha (IL-5 receptor subunit alpha) (IL-5R subunit alpha) (IL-5R-alpha) (IL-5RA) (CDw125) (CD antigen CD125)
Gene: IL5RA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.961 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10823900, 7957082, 7721873, 1732409, 22153509, 1495999 |
| Identification Methods | pull down, molecular sieving, surface plasmon resonance, x-ray crystallography, cross-linking study, protein cross-linking with a bifunctional reagent, cosedimentation in solution, isothermal titration calorimetry, saturation binding |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL5~IL6Ra-bind |
| Common GO terms | GO:0005615 - extracellular space GO:0038043 - interleukin-5-mediated signaling pathway |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
