Protein: UBP6
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2) (RN-tre) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)

Gene: UBP6, USP6
Organism: Homo sapiens
Interactions: 23
UniProt ID: P35125

Gene Ontology (top 5):
GO:0003676 - nucleic acid binding
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

762701

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

13

High-throughput

0.691

High

507596

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

18

High-throughput

0.647

High

762694

CDC42
Cell division control protein 42 homolog

1

14

Small-scale

0.647

High

762696

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

Small-scale

0.647

High

762698

AT7L3
Ataxin-7-like protein 3

1

1

High-throughput

0.625

High

762704

RB33B
Ras-related protein Rab-33B

1

4

Small-scale

0.621

High

533988

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

2

Small-scale

0.586

High

762702

EXOS8
Exosome complex component RRP43

2

1

High-throughput

0.584

High

762703

MDFI
MyoD family inhibitor

1

1

High-throughput

0.560

High

762700

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

1

3

Small-scale

0.535

High

429394

JUN
Transcription factor Jun

1

4

Small-scale

0.512

High

421598

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

658641

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.501

High

762705

CABP2
Calcium-binding protein 2

1

2

High-throughput

0.481

High

762707

TFP11
Tuftelin-interacting protein 11

1

3

High-throughput

0.481

High

169976

AURKA
Aurora kinase A

1

8

Small-scale

0.479

High

403868

GCR
Glucocorticoid receptor

1

10

High-throughput

0.479

High

762695

ARF6
ADP-ribosylation factor 6

1

4

Small-scale

0.479

High

762706

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

762697

RIPP1
Protein ripply1

1

1

High-throughput

0.439

High

762699

ANR11
Ankyrin repeat domain-containing protein 11

1

4

High-throughput

0.439

High

216879

KLF4
Krueppel-like factor 4

1

2

Small-scale

0.437

High

762693

ZNF76
Zinc finger protein 76

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025