HitPredict

Interactor 1: KPCG (P05129)
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)
Gene: PRKCG

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20395553
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 697 Hs			1 840
+	Hs
		408567 KPCB_HUMAN (1-681): 0: 716: 67.79		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		681688 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		320923 KS6B2_HUMAN (290-695): 2.01e-149: 444: 36.43		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		1267772 KS6B2_HUMAN (290-695): 2.01e-149: 444: 36.43		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		714196 KPCD_HUMAN (3-166): 8.84e-63: 223: 38.60		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Sc
		623445 KPC1_YEAST (17-680): 0: 556: 28.24		HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61
+	Hs
		397128 KPCG_HUMAN (1-697): 0: 772: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		397134 KPCG_HUMAN (1-697): 0: 772: 100.00		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		503390 KPCA_HUMAN (1-683): 0: 725: 70.03		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		503528 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		504896 KS6B2_HUMAN (290-695): 2.01e-149: 444: 36.43		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		564016 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		564201 KS6B2_HUMAN (290-695): 2.01e-149: 444: 36.43		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		503922 KPCE_HUMAN (3-262): 3.13e-57: 209: 34.07		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Mm
		554912 KPCE_MOUSE (3-245): 3.78e-57: 208: 35.16		HS71A_MOUSE (571-686): 1e-17: 89.7: 23.08
+	Hs
		503600 KPCI_HUMAN (6-85): 1.85e-12: 72.4: 39.29		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		503948 KPCZ_HUMAN (21-85): 2.64e-10: 65.5: 36.92		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		564026 KPCI_HUMAN (6-85): 1.85e-12: 72.4: 39.29		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		564062 KPCZ_HUMAN (21-85): 2.64e-10: 65.5: 36.92		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86