Protein: MCR
Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2)

Gene: MCR, NR3C2
Organism: Homo sapiens
Interactions: 41
UniProt ID: P08235

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0003707 - nuclear steroid receptor activity
GO:0004879 - nuclear receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

467790

NCOA1
Nuclear receptor coactivator 1

3

20

Small-scale

0.839

High

403749

GCR
Glucocorticoid receptor

2

20

Small-scale

0.783

High

467792

CARME
Carnosine N-methyltransferase

4

1

High-throughput

0.691

High

180667

TIF1A
Transcription intermediary factor 1-alpha

3

20

Small-scale

0.651

High

467805

FAF1
FAS-associated factor 1

2

8

Small-scale

0.649

High

467774

RXRA
Retinoic acid receptor RXR-alpha

1

20

High-throughput

0.621

High

461046

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

467772

MCR
Mineralocorticoid receptor

1

19

High-throughput

0.618

High

467773

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

467782

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

20

Small-scale

0.618

High

467788

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

20

Small-scale

0.618

High

467801

DAXX
Death domain-associated protein 6

1

4

Small-scale

0.552

High

467791

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

9

High-throughput

0.536

High

467806

MTL5
Tesmin

1

1

Small-scale

0.529

High

467787

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.515

High

467799

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

467800

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

20

Small-scale

0.506

High

467802

PRAF1
Prenylated Rab acceptor protein 1

1

2

High-throughput

0.494

High

467775

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

6

High-throughput

0.481

High

467779

PRS8
26S proteasome regulatory subunit 8

1

20

High-throughput

0.481

High

467780

SUMO1
Small ubiquitin-related modifier 1

1

15

Small-scale

0.481

High

467781

UBC9
SUMO-conjugating enzyme UBC9

1

13

Small-scale

0.481

High

467793

PROX1
Prospero homeobox protein 1

1

3

High-throughput

0.481

High

467803

C8AP2
CASP8-associated protein 2

1

1

Small-scale

0.481

High

122903

SGK1
Serine/threonine-protein kinase Sgk1

1

18

Small-scale

0.479

High

124721

AIP
AH receptor-interacting protein

1

20

Small-scale

0.479

High

467776

NRIP1
Nuclear receptor-interacting protein 1

1

19

Small-scale

0.479

High

467777

PPP5
Serine/threonine-protein phosphatase 5

1

20

Small-scale

0.479

High

467778

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

14

Small-scale

0.479

High

467783

CAV1
Caveolin-1

1

5

Small-scale

0.479

High

467784

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

467785

UBE3A
Ubiquitin-protein ligase E3A

1

20

Small-scale

0.479

High

467786

PPID
Peptidyl-prolyl cis-trans isomerase D

1

8

Small-scale

0.479

High

467789

TEBP
Prostaglandin E synthase 3

1

8

Small-scale

0.479

High

467794

CBP
CREB-binding protein

1

20

Small-scale

0.479

High

467795

KAT2A
Histone acetyltransferase KAT2A

1

20

Small-scale

0.479

High

467796

KAT2B
Histone acetyltransferase KAT2B

1

20

Small-scale

0.479

High

467797

T22D3
TSC22 domain family protein 3

1

1

Small-scale

0.479

High

467798

DNJC7
DnaJ homolog subfamily C member 7

1

20

Small-scale

0.479

High

467804

CHIP
E3 ubiquitin-protein ligase CHIP

1

20

Small-scale

0.479

High


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Last updated: 11Aug2025