HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: GRP75 (P48721)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (Peptide-binding protein 74) (PBP74) (mtHSP70)
Gene: Hspa9

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0019899 - enzyme binding GO:0031072 - heat shock protein binding GO:0051087 - protein-folding chaperone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 752 Rn			1 679
+	Rn
		94098 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		F1M953_RAT (1-679): 0: 861: 99.71
+	Mm
		497989 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		HSP7C_MOUSE (51-653): 0: 872: 50.00
+	Mm
		497918 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		HS71L_MOUSE (49-677): 0: 871: 46.97
+	Mm
		498048 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		HS71A_MOUSE (51-672): 0: 861: 47.13
+	Mm
		497919 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		HSP72_MOUSE (50-669): 0: 859: 48.03
+	Hs
		496425 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		HS71L_HUMAN (51-677): 0: 875: 47.43
+	Hs
		496165 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		HSP7C_HUMAN (51-653): 0: 873: 50.00
+	Hs
		496242 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		HSP76_HUMAN (49-674): 0: 869: 48.36
+	Hs
		496467 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		GRP75_HUMAN (1-679): 0: 867: 98.09
+	Hs
		483743 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		HS71A_HUMAN (51-652): 0: 866: 48.94
+	Hs
		496637 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		HSP72_HUMAN (50-653): 0: 863: 48.79
+	Hs
		503487 MAP4_HUMAN (9-727): 1.28e-34: 144: 19.84		HSP7C_HUMAN (51-653): 0: 873: 50.00
+	Hs
		503916 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		HSP7C_HUMAN (51-653): 0: 873: 50.00
+	Hs
		483759 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		HS71A_HUMAN (51-652): 0: 866: 48.94
+	Rn
		419259 TAU_RAT (1-752): 2.4e-95: 314: 100.00		BIP_RAT (53-677): 0: 566: 51.81
+	Rn
		94115 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		BIP_RAT (53-677): 0: 566: 51.81
+	Hs
		496163 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		BIP_HUMAN (53-677): 0: 566: 50.39
+	Hs
		501722 MAP4_HUMAN (9-727): 1.28e-34: 144: 19.84		BIP_HUMAN (53-677): 0: 566: 50.39
+	Hs
		91549 E7EVA0_HUMAN (179-727): 1.78e-30: 131: 21.90		BIP_HUMAN (53-677): 0: 566: 50.39
+	Hs
		501987 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		BIP_HUMAN (53-677): 0: 566: 50.39