HitPredict

Interactor 1: ADT2 (P05141)
ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]
Gene: SLC25A5

Interactor 2: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 745
+	Hs
		397378 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		397381 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		518344 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		397382 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		518346 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		397380 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		518345 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		397464 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		CUL5_HUMAN (7-745): 0: 627: 26.69
+	Hs
		1042795 S2513_HUMAN (2-104): 5.95e-22: 97.6: 27.18		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1042436 SCMC3_HUMAN (4-99): 3.11e-16: 80.2: 15.63		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Sc
		576025 ADT2_YEAST (207-297): 5.21e-12: 67.1: 26.32		CDC53_YEAST (5-745): 0: 622: 25.94
+	Sp
		998261 ADT_SCHPO (200-297): 9.12e-11: 63.3: 22.55		CUL3_SCHPO (8-745): 0: 620: 23.84